Fetal heart rate and tissue pH changes associated with repetitive aortic occlusion in the pregnant dog

American Journal of Obstetrics and Gynecology
M M Abitbol


Variations in fetal heart rate (FHR) and tissue pH (tpH) were studied simultaneously in 10 pregnant dogs at term during experimental fetal distress produced by subjecting the fetuses to short episodes of acute anoxia, which was produced by occlusion of thr maternal aorta. The fetal response to these anoxic episodes dependent on the initial value of the tpH. With tpH higher than or equal to 7.20, the tpH and FHR showed minimal or no response. With tpH between 7.20 and 7.10, the FHR showed a "delayed" deceleration and there was a sharp decline in tpH. With lower tpH, the variations in FHR and tpH were less accentuated. Also noted were unusual variations, such as "transient" or "irregular" FHR decelerations, and tpH "reactive alkalosis." In this acute experimental situation, tpH seemed to be a very sensitive indicator of fetal anoxia. The combined continuous monitoring of FHR and tpH for the diagnosis of fetal distress deserves further investigation.

Related Concepts

Abdominal Aorta Structure
Canis familiaris
Implantable Stimulation Electrodes
Fetal Hypoxia
Fetal Heart
Pulse Rate
Hydrogen-Ion Concentration
Regional Blood Flow

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Archaeal RNA Polymerase

Archaeal RNA polymerases are most similar to eukaryotic RNA polymerase II but require the support of only two archaeal general transcription factors, TBP (TATA-box binding protein) and TFB (archaeal homologue of the eukaryotic general transcription factor TFIIB) to initiate basal transcription. Here is the latest research on archaeal RNA polymerases.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.