PMID: 45501Apr 1, 1978

Fetal response to periodic sleep apnea: a new syndrome in obstetrics

European Journal of Obstetrics, Gynecology, and Reproductive Biology
S J Joel-Cohen, A Schoenfeld


Periodic sleep apnea, a chronic sleep deprivation state, in which marked changes in the arterial PO2 and PCO2 tensions have been recorded, is a relatively new syndrome not previously reported in pregnancy. It is characterized by episodes of apnea, prevalently obstructive, during sleep. The majority of patients with this syndrome have snored heavily for years, suggesting a causal relationship between snoring and periodic sleep apnea. The effects of prolonged snoring on alveolar ventilation and systemic pressure(s) suggest that this snoring has physiopathological implications on maternal cardio-respiratory reserve and indirectly upon the fetus, especially as there are recordable changes in fetal heart rate and also a change in the acid-base status of the fetus. The possibility that this syndrome may have an adverse effect upon the fetus is stressed.


Mar 26, 2011·Archives of Gynecology and Obstetrics·Norma Amador-Licona, Juan M Guízar-Mendoza
Aug 22, 2012·Sleep & Breathing = Schlaf & Atmung·Ihunnaya O FrederickMichelle A Williams
May 23, 2001·BJOG : an International Journal of Obstetrics and Gynaecology·K A BrainA O Johnson
Aug 1, 1996·Obstetrical & Gynecological Survey·L A Lefcourt, J F Rodis
Oct 10, 2003·Current Opinion in Pulmonary Medicine·Pradeep K SahotaRajiv Dhand
May 31, 2002·Thorax·N EdwardsC E Sullivan
Nov 2, 2002·American Journal of Respiratory and Critical Care Medicine·Bilgay IzciNeil J Douglas
Mar 11, 2003·American Journal of Respiratory and Critical Care Medicine·David GozalAndrew J Lipton
Aug 27, 2014·Clinics in Chest Medicine·Dennis OyiengoGhada Bourjeily
Feb 1, 2011·Clinics in Chest Medicine·Ghada BourjeilyVahid Mohsenin
May 1, 1996·American Journal of Obstetrics and Gynecology·E NikkolaO Polo
Apr 1, 1996·Chest·M R Littner
Dec 8, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Shanthi CarnelioH David McIntyre
Nov 3, 2007·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Figen Kir SahinMehmet Unlu
May 5, 2012·Therapeutic Advances in Respiratory Disease·Ghada BourjeilyKathleen O'Connor
Jan 25, 2018·Expert Review of Respiratory Medicine·Kimberly Kay Truong, Christian Guilleminault
Apr 13, 2018·Anesthesia and Analgesia·Jennifer E DominguezAshraf S Habib
Sep 1, 2009·Obstetric Medicine·Ghada Bourjeily

Related Concepts

Carbon Dioxide
Fetal Monitoring
Fetal Structures
Heart Rate, Fetal
Hydrogen-Ion Concentration
Obesity Hypoventilation Syndrome
Pregnancy Complications

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Synthetic Genetic Array Analysis

Synthetic genetic arrays allow the systematic examination of genetic interactions. Here is the latest research focusing on synthetic genetic arrays and their analyses.

Congenital Hyperinsulinism

Congenital hyperinsulinism is caused by genetic mutations resulting in excess insulin secretion from beta cells of the pancreas. Here is the latest research.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Epigenetic Memory

Epigenetic memory refers to the heritable genetic changes that are not explained by the DNA sequence. Find the latest research on epigenetic memory here.

Cell Atlas of the Human Eye

Constructing a cell atlas of the human eye will require transcriptomic and histologic analysis over the lifespan. This understanding will aid in the study of development and disease. Find the latest research pertaining to the Cell Atlas of the Human Eye here.

Femoral Neoplasms

Femoral Neoplasms are bone tumors that arise in the femur. Discover the latest research on femoral neoplasms here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.