Fetal sex determination using cell-free fetal DNA: service users' experiences of and preferences for service delivery.

Prenatal Diagnosis
Celine LewisLyn S Chitty

Abstract

The aim of this study was to determine service users' experiences of and preferences for service delivery of fetal sex determination by noninvasive prenatal diagnosis (NIPD) using cell-free fetal DNA. We used a qualitative approach using semistructured interviews. Thirty-eight women and six of their partners were recruited. NIPD was viewed as a positive development, which facilitated reproductive autonomy as it expanded reproductive choice. The majority of women heard about NIPD during pregnancy and had received information about the test at a specialist centre. Features of NIPD women considered most important were that it could be performed early in pregnancy and was safe. Participants had a preference for being given information about NIPD and test results by a healthcare professional experienced in genetic testing and with specialist knowledge about their condition, rather than a general practitioner or midwife who may not have the same level of knowledge. Women also valued receiving their test results by telephone. Women were overwhelmingly positive about their experience of NIPD, which suggests that current delivery of this service in England is acceptable to these patients who are at high risk of sex-linked genetic disord...Continue Reading

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Citations

Nov 29, 2012·European Journal of Human Genetics : EJHG·Zuzana DeansCeline Lewis
Jun 1, 2013·Journal of Genetic Counseling·Joanne B TaylorLouanne Hudgins
Mar 7, 2014·Best Practice & Research. Clinical Obstetrics & Gynaecology·Lyn S Chitty
Sep 12, 2013·European Journal of Human Genetics : EJHG·Heather SkirtonLyn Chitty
Apr 10, 2014·Journal of Genetic Counseling·Lauren C SayresMildred K Cho
Oct 23, 2016·Journal de gynécologie, obstétrique et biologie de la reproduction·O AnselemV Tsatsaris
Nov 8, 2012·Journal of Pediatric Urology·Lyn S ChittyYves Aigrain
May 1, 2012·Best Practice & Research. Clinical Obstetrics & Gynaecology·Melissa HillLyn S Chitty
May 21, 2013·Prenatal Diagnosis·Lyn S Chitty, Diana W Bianchi
Feb 20, 2014·Health Expectations : an International Journal of Public Participation in Health Care and Health Policy·Caroline SilcockLyn S Chitty
Jun 30, 2015·Genetic Testing and Molecular Biomarkers·Rintu Rebecca JacobIshwar Chander Verma
Feb 26, 2015·Journal of Perinatology : Official Journal of the California Perinatal Association·J I IruretagoyenaD Shah
Apr 29, 2020·International Journal of Technology Assessment in Health Care·Yan WeiYingyao Chen
Feb 13, 2016·Current Opinion in Obstetrics & Gynecology·Melissa HillLyn S Chitty
May 30, 2013·Prenatal Diagnosis·Mark I EvansDavid W Britt
Apr 10, 2020·Journal of Thrombosis and Haemostasis : JTH·Marieke C PuntKarin P M van Galen
Oct 30, 2014·Current Opinion in Endocrinology, Diabetes, and Obesity·Berenice B Mendonca

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