PMID: 11336767May 5, 2001Paper

Fetal splenic rupture following transfusion

Obstetrics and Gynecology
P W WhitecarK J Moise

Abstract

Splenic rupture in the newborn is a rare complication in erythroblastosis fetalis. There are no reports of splenic rupture in the fetus affected by hemolytic disease of the newborn. A 41-year-old gravida 3, para 2-0-0-2 with severe rhesus alloimmunization was managed with serial intrauterine transfusions resulting in fetal death after the fourth procedure. Autopsy findings revealed intra-abdominal clotted blood and splenic capsular defects consistent with splenic rupture. Fetal splenic rupture might occur in hemolytic disease of the newborn associated with splenomegaly. Acute hemodynamic changes with increased intra-abdominal pressure from intrauterine transfusion might precipitate splenic rupture. (Obstet Gynecol 2001;97:824-5.

References

May 1, 1975·Archives of Disease in Childhood·J B Coulter, P A Raine
Mar 1, 1972·The Journal of Pediatrics·L Fenton, K E Bove
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·F J KlumperH H Kanhai
Feb 3, 1955·The New England Journal of Medicine·H F PHILIPSBORND GREER

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Citations

Sep 17, 2004·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·S C RaoD A Doherty

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