Fetal Thrombotic Vasculopathy: Perinatal Stroke, Growth Restriction, and Other Sequelae

Surgical Pathology Clinics
F T Kraus

Abstract

Clots in the fetal circulation of the placenta may occlude or narrow the lumens of fetal vessels sufficiently to diminish the placental oxygen and nutritional exchange, causing significant reduction in placental function. When extensive, growth restriction, neonatal encephalopathy, and stillbirth may occur. Propagation of clots in other organs, such as brain, kidney, and liver, may affect the function of these organs, resulting in infarcts and neonatal stroke. This article presents an account of the placental pathology and clinical sequelae of this condition, called fetal thrombotic vasculopathy.

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Citations

Mar 25, 2017·Blood Cells, Molecules & Diseases·Ryan J FellingTimothy Bernard
Apr 27, 2019·Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·Maria Garrido-BarberoAlfredo Garcia-Alix
Apr 3, 2020·Journal of Perinatal Medicine·Sunil JaimanChaur-Dong Hsu
Jun 10, 2020·Journal of Child Neurology·Bithi RoyIona Novak
Jun 15, 2016·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Frederick T Kraus, Thomas M Ulbright

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Methods Mentioned

BETA
imaging techniques
dissect

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