Fever in Children and Fever of Unknown Origin

Indian Journal of Pediatrics
Rajeshwar Dayal, Dipti Agarwal

Abstract

Fever is the most common symptom in children and can be classified as fever with or without focus. Fever without focus can be less than 7 d and is subclassified as fever without localizing signs and fever of unknown origin (FUO). FUO is defined as a temperature greater than 38.3 °C, for more than 3 wk or failure to reach a diagnosis after 1 wk of inpatient investigations. The most common causes of FUO in children are infections, connective tissue disorders and neoplasms. Infectious diseases most commonly implicated in children with FUO are salmonellosis, tuberculosis, malaria and rickettsial diseases. Juvenile rheumatic arthritis is the connective tissue disease frequently associated with FUO. Malignancy is the third largest group responsible for FUO in children. Diagnostic approach of FUO includes detailed history and examination supported with investigations. Age, history of contact, exposure to wild animals and medications should be noted. Examination should include, apart from general appearance, presence of sweating, rashes, tonsillitis, sinusitis and lymph node enlargement. Other signs such as abdominal tenderness and hepatosplenomegly should be looked for. The muscles and bones should be carefully examined for connective...Continue Reading

References

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Citations

Feb 19, 2016·Iranian Red Crescent Medical Journal·Mohammad Reza SharifMasoud Rangraz
Sep 19, 2019·Revista da Associação Médica Brasileira·Leonardo Fernandes E SantanaOrlando Vieira Gomes
Jun 4, 2019·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Ryo SugawaraKatsushi Takeshita
Nov 14, 2019·Revista da Associação Médica Brasileira·Leonardo Fernandes E SantanaOrlando Vieira Gomes
Feb 20, 2016·La Radiologia medica·Maria Beatrice DamasioGiorgio Stagnaro
Jul 14, 2020·Cardiology in the Young·Alvaro DonaireGarciaHemant S Agarwal

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