Fever of unknown origin: 98 cases from Saudi Arabia.

Annals of Saudi Medicine
Mahmoud A MoawadUlrike Laudon

Abstract

Fever of unknown origin (FUO) is mainly secondary to infectious, neoplastic or inflammatory diseases. To increase the body of knowledge on this diagnosis in the region, we collected information on all patients admitted to our institution with FUO in a 13-year period. We conducted a retrospective chart review of all immunocompetent males and females aged 13 years and older admitted between January 1995 and June 2008 who fulfilled the criteria for FUO. Data collection included demographics, laboratory investigations, imaging studies, procedures and discharge diagnoses. For true FUO, we recorded the duration of follow-up and the outcome. The 98 patients who met the criteria included 44 males and 54 females with a mean (SD) age of 41.3 (18.5) years and range of 14 to 85 years. The most frequent diagnostic etiology was infectious in 32 (32.7%). Seventeen (17.3%) patients were undiagnosed or had true FUO. Of 9 patients followed up, 8 recovered and 1 expired. The mean duration of follow-up was 20.6 months (range, 0-168 months). Infectious diseases, especially TB, continue to be the leading etiology of FUO in our area. Our data did not identify any predictor of certain FUO diagnoses except for older age and neoplastic etiology. True FU...Continue Reading

References

Oct 1, 1992·The Surgical Clinics of North America·J Sackier
Jan 1, 1992·Archives of Internal Medicine·R G Petersdorf
Jun 1, 1988·Journal of the Royal Society of Health·A A Al-NasserA K Al-Aska
Oct 9, 1995·Archives of Internal Medicine·E M de KleijnJ W van der Meer
Mar 25, 1996·Archives of Internal Medicine·D C KnockaertH J Bobbaers
Dec 23, 1998·Nuclear Medicine Communications·S GratzW Becker
Mar 9, 2000·Hospital Medicine·E M Prvulovich, S R Underwood
Mar 8, 2003·Archives of Internal Medicine·Ophyr MouradAllan S Detsky
Aug 16, 2003·European Journal of Internal Medicine·Cristian BaicusAnda Baicus
Feb 1, 1961·Medicine·R G PETERSDORF, P B BEESON
Jan 20, 2004·European Journal of Nuclear Medicine and Molecular Imaging·Andreas KjaerLiselotte Højgaard
Jan 22, 2004·Infection·F TabakY Aktuglu
Jul 17, 2007·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Yasar KucukardaliUNKNOWN Fever of Unknown Origin Study Group
Aug 19, 2007·The American Journal of the Medical Sciences·Aylin ColpanHurrem Bodur

❮ Previous
Next ❯

Citations

Jun 13, 2013·International Journal of Immunopathology and Pharmacology·D Rigante, S Esposito

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray
biopsy

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.