Fever of unknown origin: attempts to isolate L-forms and other aberrant bacterial forms.

Journal of Clinical Microbiology
R GleckmanS Madoff

Abstract

An investigation was conducted with 65 selected febrile patients, 33 of whom fulfilled in all respects the classic criteria of "fever of unknown origin." Clinical evaluation included extensive radiological and immunological testing. Multiple blood cultures were examined by conventional methods in control studies. In addition, venous blood was cultured in a variety of hyperosmolar media using the special techniques used to detect L-forms and other cell wall-defective bacterial forms. By the extensive methods used, no bacterial forms were isolated. The use of media containing osmotic stabilizers did not detect L-forms or other aberrant bacterial forms, nor did it contribute to the determination of the etiology of fever of unknown origin in these patients.

References

Jul 11, 1975·The American Journal of Medicine·R S IrwinB J Enegren
Nov 1, 1974·American Journal of Clinical Pathology·J P PhairJ Carleton
Dec 27, 1973·The New England Journal of Medicine·G A Jacoby, M N Swartz
Nov 1, 1970·Journal of Medical Microbiology·S W Newsom
Jan 1, 1958·Proceedings of the Society for Experimental Biology and Medicine·J R WARDL DIENES
Feb 1, 1961·Medicine·R G PETERSDORF, P B BEESON
Jan 15, 1960·Annals of the New York Academy of Sciences·S MADOFF

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Citations

Sep 1, 1980·The American Journal of Medicine

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