PMID: 7013908May 18, 1981Paper

Fever response in the guinea pig before and after parturition

Brain Research
E ZeisbergerS Blähser

Abstract

The febrile response to an intramuscular injection of bacterial endotoxin (E. coli 4 microgram/kg) was tested in guinea pigs at the end of pregnancy in the time period extending from 8 days before until 3 days after parturition. In comparison to non-pregnant female controls both fever height and fever index were reduced in mother guinea pigs one week before parturition. This response was gradually reduced and reached its minimum on the last day before parturition. Immediately after parturition the fever response was still suppressed in mother animals as well as in newborns. Several hours after birth the fever response increased again in both groups of animals. The onset time and duration of fever were, however, shorter than in controls. The full fever responsivity was not reached until several days postpartum. Apparently the guinea pig develops an active antipyresis during the last phase of pregnancy. This resembles the suppression of fever in ewes at term of pregnancy where endogenous arginine-vasopressin has been proposed as an antipyretic agent. The vasopressinergic neuronal systems have therefore been localized by immunohistochemical methods in the brains of the guinea pigs whose responses to bacterial endotoxin were studie...Continue Reading

References

Feb 15, 1979·Experientia·N W KastingW L Veale
Sep 17, 1976·Science·E SatinoffB A Williams
Aug 1, 1974·Toxicology and Applied Pharmacology·C M Blatteis
Nov 1, 1973·Canadian Journal of Physiology and Pharmacology·Q J PittmanG R Van Petten
May 1, 1974·Clinical Science and Molecular Medicine·Q J PittmanG R Van Petten
Aug 1, 1954·Proceedings of the Society for Experimental Biology and Medicine·R T SMITH, L THOMAS
Apr 1, 1962·The Journal of Experimental Medicine·J W UHR

❮ Previous
Next ❯

Citations

Jul 1, 1992·Pflügers Archiv : European journal of physiology·K GoelstH Laburn
Mar 1, 1992·Pflügers Archiv : European journal of physiology·K GoelstH Laburn
Aug 1, 1988·Pflügers Archiv : European journal of physiology·E ZeisbergerE Simon
Dec 15, 1983·Experientia·S B Kandasamy, B A Williams
Jan 1, 1982·Neuroscience and Biobehavioral Reviews·N W KastingK E Cooper
Jan 1, 1982·Pharmacology & Therapeutics·R Hellon, Y Townsend
Jan 1, 1983·Pharmacology & Therapeutics·W G Clark, J M Lipton
Jan 1, 1983·Pharmacology & Therapeutics·G P KozlowskiE A Zimmerman
Aug 1, 1988·Brain Research·H H Zingg, D L Lefebvre
Mar 1, 1988·Neuroscience·M Castel, J F Morris
Oct 14, 2003·Experimental Neurology·Marie Stéphanie Clerget-Froidevaux, Quentin J Pittman
Feb 1, 1996·Journal of Neuroendocrinology·S M MartinQ J Pittman
Jan 26, 1999·Annals of the New York Academy of Sciences·Q J PittmanS Martin
Jan 26, 1999·Annals of the New York Academy of Sciences·B CannonJ Nedergaard
Feb 3, 2006·Journal of Neuroendocrinology·E-M HarréQ J Pittman
Feb 13, 2008·Journal of Neuroendocrinology·A MouihateQ J Pittman
Mar 22, 2006·Clinica Chimica Acta; International Journal of Clinical Chemistry·Joachim Roth
Jan 1, 1993·Neuroscience and Biobehavioral Reviews·H Moltz
Dec 2, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·H AshdownG N Luheshi
Mar 3, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Denovan P BeggMichael L Mathai
Feb 7, 2003·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Andrei I Ivanov, Andrej A Romanovsky
Oct 22, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Kyoko Imai-MatsumuraYasuyoshi Watanabe
Aug 20, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·A MouihateQ J Pittman
Feb 1, 1984·Brain Research Bulletin·W L VealeW D Ruwe

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.