FGF-2: specific activity in kidney?

Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. RTKs have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Discover the latest research on cell signaling and RTK here.

FGF-2: specific activity in kidney?

Abstract

References

Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex

Developmental regulation of neural response to FGF-1 and FGF-2 by heparan sulfate proteoglycan

Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy

Cryptic physiological trophic support of motoneurons by LIF revealed by double gene targeting of CNTF and LIF

Fibroblast growth factor signalling in the hair growth cycle: expression of the fibroblast growth factor receptor and ligand genes in the murine hair follicle

Characterization and tissue-specific expression of the rat basic fibroblast growth factor antisense mRNA and protein

sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways

Fibroblast growth factor 2 control of vascular tone

Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning

Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney.

Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

Localization of fibroblast growth factor-2 (basic FGF) and FGF receptor-1 in adult human kidney

Citations

Bone ingrowth in bFGF-coated hydroxyapatite ceramic implants

Fibroblast growth factor receptors and their ligands in the adult rat kidney

FGF/EGF signaling regulates the renewal of early nephron progenitors during embryonic development.

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