FGF2: a key regulator augmenting tendon-to-bone healing and cartilage repair.

Regenerative Medicine
Jun ZhangYi Liu

Abstract

Ligament/tendon and cartilage injuries are clinically common diseases that perplex most clinicians. Because of the lack of blood vessels and nerves, their self-repairing abilities are rather poor. Therefore, surgeries are necessary and also widely used to treat ligament/tendon or cartilage injuries. However, after surgery, there are still many problems that affect healing. In recent years, it has been found that exogenous FGF2 plays an important role in the repair of ligament/tendon and cartilage injuries and exerts a synergistic effect with endogenous FGF2. Therefore, FGF2 can be used as a new type of biomolecule to accelerate tendon-to-bone healing and cartilage repair after injury.

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Citations

Jan 6, 2021·Journal of Nanobiotechnology·Hamed NosratiZohreh Alizadeh
Jul 30, 2021·Advanced Drug Delivery Reviews·Yaping Zhuang, Wenguo Cui

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