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FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in ES cells

bioRxiv

Feb 18, 2015

Christian SchröterAlfonso Martinez Arias

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Abstract

Intracellular transcriptional regulators and extracellular signaling pathways together regulate the allocation of cell fates during development, but how their molecular activities are integrated to establish the correct proportions of cells with particular fates is not known. Here we st...read more

Mentioned in this Paper

Gene Expression
Transcriptional Regulation
Blastocyst Structure
GATA Transcription Factors
Signal Transduction Pathways
Biochemical Pathway
Extracellular
Signal Pathways
Signal Transduction
Embryo
9
46
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  • FGF/MAPK signaling sets the switching threshold of a bistable circuit controlling cell fate decisions in ES cells

    bioRxiv

    Feb 18, 2015

    Christian SchröterAlfonso Martinez Arias

    PMID: 990015404

    DOI: 10.1101/015404

    Abstract

    Intracellular transcriptional regulators and extracellular signaling pathways together regulate the allocation of cell fates during development, but how their molecular activities are integrated to establish the correct proportions of cells with particular fates is not known. Here we st...read more

    Mentioned in this Paper

    Gene Expression
    Transcriptional Regulation
    Blastocyst Structure
    GATA Transcription Factors
    Signal Transduction Pathways
    9
    46

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