Fibrin glue as a drug delivery system.

Journal of Controlled Release : Official Journal of the Controlled Release Society
Patrick P Spicer, Antonios G Mikos

Abstract

Fibrin glue has been used surgically for decades for hemostasis as well as a sealant. It has also been researched as both a gel for cell delivery and a vehicle for drug delivery. The drug delivery applications for fibrin glue span tissue engineering to chemotherapy and involve several mechanisms for drug matrix interactions and control of release kinetics. Additionally, drugs or factors can be loaded in the gel via impregnation and tethering to the gel through covalent linkages or affinity-based systems. This review highlights recent research of fibrin glue as a drug delivery vehicle.

References

Oct 1, 1992·The Journal of Surgical Research·C M PipanW D Spotnitz
Apr 1, 1992·Journal of Biomedical Materials Research·C FlahiffS Huang
Aug 1, 1985·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·H Matras
Sep 19, 1997·Journal of Biomedical Materials Research·K FujimotoY Nimura
Apr 29, 1998·The Journal of Biological Chemistry·A SahniC W Francis
Oct 9, 1999·The Journal of Biological Chemistry·P G CampbellD R Powell
Mar 22, 2000·Biological & Pharmaceutical Bulletin·H YoshidaA Kamiya
Mar 12, 2004·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Hugo SchmoekelJeffrey A Hubbell
Dec 25, 2004·Biotechnology and Bioengineering·Hugo G SchmoekelJeffrey A Hubbell
Jul 11, 2006·The Spine Journal : Official Journal of the North American Spine Society·Vikas V PatelRick B Delamarter
May 10, 2008·Journal of Biomedical Materials Research. Part a·Ailish BreenAbhay Pandit
May 10, 2008·Journal of Biomedical Materials Research. Part a·Matthew D WoodShelly E Sakiyama-Elbert
Jun 5, 2008·The Journal of Pharmacology and Experimental Therapeutics·Lorraine YauPeter Zahradka
Jun 12, 2008·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Wenxue ZhaoJianwu Dai
Jan 7, 2009·Biomaterials·Isabelle ArrighiJason C Schense
Feb 24, 2009·Aesthetic Surgery Journal·Xiao Zhibo, Zhang Miaobo
Mar 10, 2009·Drug Delivery·T J MortonH Redl
Apr 23, 2009·Stem Cell Research·Stephanie M WillerthShelly E Sakiyama-Elbert
Jun 25, 2009·Journal of Neurotrauma·Ming-Chao HuangHenrich Cheng
Aug 8, 2009·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Jon E MogfordThomas A Mustoe

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Citations

Mar 30, 2011·Journal of Materials Science. Materials in Medicine·Wenjun ZhouYan Mou
Apr 15, 2011·Journal of Drug Delivery·Maluta S MufamadiValence M K Ndesendo
Jul 3, 2013·Tissue Engineering. Part B, Reviews·Henning MadryMagali Cucchiarini
Nov 29, 2013·Surgical Infections·Hidemasa NakaminamiNorihisa Noguchi
Dec 3, 2013·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Shinichi OzakiNoboru Motomura
Jul 19, 2013·Stem Cells International·Julia van de KampSabine Neuss
May 1, 2013·Journal of Biomedical Materials Research. Part a·Emmanuel E SadavaYuri W Novitsky
Aug 9, 2012·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Yong HanHongchen Liu
Nov 26, 2011·Journal of Controlled Release : Official Journal of the Controlled Release Society·Eduardo Anitua, Gorka Orive
Oct 27, 2010·Journal of Controlled Release : Official Journal of the Controlled Release Society·Fa-Ming ChenMin Zhang
Aug 2, 2015·International Journal of Biological Macromolecules·Ejaj AhmadMohammed Saleemuddin
Apr 25, 2012·Clinical Oral Implants Research·Florian G DraenertWilfried Wagner
Feb 20, 2013·Macromolecular Bioscience·Marie-Cécile KlakVéronique Larreta-Garde
Mar 18, 2011·Journal of Tissue Engineering and Regenerative Medicine·Hai-Hua SunFa-Ming Chen
Apr 18, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Martin KaipelHeinz Redl
Jan 9, 2013·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Feng ChenXian H Zhu
Mar 29, 2014·Cancer Science·Shigeo AnaiJun-ichi Kuratsu
Feb 7, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Munazza T FatimaMohammed Saleemuddin
Jun 18, 2014·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Allan M HensleeAntonios G Mikos
Dec 15, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·D DuttaS E Stabenfeldt
Apr 10, 2016·Advanced Materials·Jianhua LiYounan Xia
Jun 9, 2015·The Journal of Clinical Investigation·Chang H LeeJeremy J Mao
Jul 16, 2013·Journal of Plastic Surgery and Hand Surgery·Hitomi SanoMiho Suzuki
Mar 19, 2013·International Journal of Pharmaceutics·Eva FilováEvžen Amler
Mar 30, 2016·Progress in Polymer Science·Fa-Ming Chen, Xiaohua Liu
Feb 12, 2015·Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association·Ramon CugatMontserrat García-Balletbó
Jul 20, 2014·Biologicals : Journal of the International Association of Biological Standardization·Weslen S Vedakumari, Thotapalli P Sastry
Nov 12, 2014·PloS One·Rajshekhar GannavarpuGabriel Popescu
Sep 7, 2016·The Journal of Hand Surgery·Leigh SundemJohn Elfar

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