Fibrin glue for all anal fistulas

Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract
S M Sentovich

Abstract

The aim of this study was to determine if a new sphincter muscle-sparing technique that uses fibrin glue was effective in closing all types of anal fistulas. All patients with anal fistulas who were seen by a single surgeon over a 2-year period were treated with fibrin glue. Six to 8 weeks after a seton was placed in the fistula tract, either autologous fibrin glue or commercially available fibrin sealant was used to close the fistula tract. Twenty patients were treated with a mean follow-up of 10 months. Etiology of the anal fistulas was as follows: cryptoglandular in 13, Crohn's disease in four, and miscellaneous in three. Fibrin glue closure of the anal fistula was successful initially in 15 patients (75%) and was successful after a second treatment in two additional patients, for an overall fibrin glue fistula closure rate of 85% (17 of 20). Functional results have remained excellent with no patient reporting any change in continence after treatment. Fibrin glue is simple and effective treatment for all anal fistulas with excellent functional results.

Citations

Mar 3, 2005·ANZ Journal of Surgery·Matthew J F X Rickard
Oct 21, 2006·Diseases of the Colon and Rectum·C Neal Ellis, Stephen Clark
Mar 12, 2008·Diseases of the Colon and Rectum·Alex J KyErin K Ly
Mar 10, 2018·Diseases of the Colon and Rectum·Oluwatomilayo O DaoduJohn A Heine
Feb 24, 2004·Diseases of the Colon and Rectum·Rasmy LoungnarathJames W Fleshman
Apr 26, 2005·Digestive Surgery·Suzanne S GisbertzMichael F Gerhards
Jan 17, 2007·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A SygutA Dziki
Aug 4, 2007·Diseases of the Colon and Rectum·Kelly M TylerStephen M Sentovich
Apr 15, 2010·Diseases of the Colon and Rectum·C Neal EllisFrancis G Greiner
Apr 11, 2012·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Veronique VittonMarc Barthet
Jan 9, 2015·International Journal of Colorectal Disease·F CadedduG Milito
Jan 28, 2006·Surgery Today·Göktürk MaralcanAvni Gökalp
Feb 16, 2005·Diseases of the Colon and Rectum·Gordon N BuchananC Richard G Cohen
Jun 14, 2005·Alimentary Pharmacology & Therapeutics·V VittonJ C Grimaud
Oct 17, 2009·Inflammatory Bowel Diseases·Hussila KeshawRichard M Day
Nov 9, 2011·Journal of the Korean Surgical Society·Göktürk MaralcanAhmet Balk
Aug 3, 2010·Techniques in Coloproctology·S PanidisG Basdanis
Aug 9, 2011·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J de OcaS Biondo
Dec 31, 2010·International Journal of Colorectal Disease·Elisabeth LippertFrank Kullmann
Mar 29, 2014·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Carlos Ramon Silveira MendesSergio Eduardo Alonso Araujo
Sep 10, 2011·Diseases of the Colon and Rectum·Nadav HaimOded Zmora
Mar 17, 2010·Arquivos De Gastroenterologia·Daniel C DaminCláudio Tarta
Jun 29, 2018·BJS Open·M J LeeUNKNOWN ENiGMA Collaborators
May 16, 2020·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·M ZelićJ Warusavitarne
Sep 1, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T M HammondP J Lunniss
Nov 30, 2012·Techniques in Coloproctology·A KucharczykK Bielecki
Dec 24, 2010·Diseases of the Colon and Rectum·C Neal Ellis
Jul 21, 2012·Journal of the Korean Society of Coloproctology·Seung Hyuk Baik, Won Ho Kim
Jun 22, 2014·Gut·Krisztina B GecseUNKNOWN World Gastroenterology Organization International Organisation for Inflammatory Bowel Diseases IOIBD European Society of Col
Nov 13, 2004·Diseases of the Colon and Rectum·Ian LindseyNeil J Mortensen
Jul 22, 2008·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·D K ThekkinkattilP J Finan
Dec 17, 2009·Diseases of the Colon and Rectum·Joshua I S BleierStanley M Goldberg
Nov 14, 2002·American Journal of Otolaryngology·Sam WisemanNestor Rigual
May 15, 2013·Journal of Visceral Surgery·C SabbaghY Panis
Feb 16, 2006·Cirugía española·Enrique CasalJosé Pampin
Nov 10, 2009·International Journal of Pediatric Otorhinolaryngology·Müslim YurtçuAdnan Abasiyanik
Jan 30, 2010·The Surgical Clinics of North America·Julie A RizzoEric K Johnson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.