Fibroblast growth factor 23: the making of a hormone

Kidney International
Susan C Schiavi

Abstract

Fibroblast growth factor 23 (FGF23) modulates serum phosphate and 1alpha,25-dihydroxyvitamin D3 levels. FGF23 expression is in turn regulated by 1alpha,25-dihydroxyvitamin D3 and dietary phosphate load, and is strikingly elevated during renal progression. In this issue, Nagano and colleagues report that FGF23 can be modulated by intermittently high dietary phosphate in the presence of compromised renal function.

References

May 10, 2001·Proceedings of the National Academy of Sciences of the United States of America·T ShimadaT Yamashita
Dec 17, 2003·Kidney International·Susan C Schiavi, Rajiv Kumar
May 27, 2005·Journal of the American Society of Nephrology : JASN·Orlando GutierrezMyles Wolf
Jun 3, 2005·Current Opinion in Nephrology and Hypertension·Masafumi FukagawaJunichiro J Kazama
Jul 16, 2005·American Journal of Physiology. Gastrointestinal and Liver Physiology·Olga I KolekFayez K Ghishan
Jul 21, 2005·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mohammed S RazzaqueBeate Lanske
Jul 22, 2005·Journal of the American Society of Nephrology : JASN·Erik A Imel, Michael J Econs

❮ Previous
Next ❯

Citations

Jan 17, 2009·Calcified Tissue International·M LarocheI Tack
Oct 8, 2008·International Urology and Nephrology·Salwa Ibrahim, Laila Rashed
Oct 31, 2006·Nature Genetics·Susan C Schiavi
Feb 8, 2008·Clinical Journal of the American Society of Nephrology : CJASN·Uri S AlonL Darryl Quarles
Dec 8, 2009·Clinical Journal of the American Society of Nephrology : CJASN·Rodrigo B OliveiraRosa M A Moysés
May 14, 2011·Journal of Pharmaceutical Sciences·Ken-ichi MiyamotoHiroko Segawa
May 20, 2008·Primary Care·Sharon M Moe
Jun 17, 2008·Molecular Aspects of Medicine·Alex J Brown, Eduardo Slatopolsky
Dec 11, 2008·Birth Defects Research. Part C, Embryo Today : Reviews·Brian L FosterMartha J Somerman
Jan 11, 2007·American Journal of Physiology. Renal Physiology·Elaine M WorcesterFredric L Coe
Jan 5, 2011·European Journal of Pediatrics·Uri S Alon
Oct 20, 2009·Gene Regulation and Systems Biology·Hiroki YokotaHugo G Ferreira
Oct 6, 2020·Frontiers in Cell and Developmental Biology·Meiheng SunFangfei Li
Nov 19, 2020·Journal of the Endocrine Society·Kathryn DahirJill H Simmons
Jul 22, 2021·Journal of the Endocrine Society·Kathryn DahirThomas Weber

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.