Fibroblast Growth Factors in Depression

Frontiers in Pharmacology
Zheng DengMi-Mi Tang

Abstract

Major depressive disorder (MDD) is one of the most serious diseases and now becomes a major public health problem in the world. The pathogenesis of depression remains poorly understood. Fibroblast growth factors (FGFs) belong to a large family of growth factors that are involved in brain development during early periods as well as maintenance and repair throughout adulthood. In recent years, studies have found a correlation between the members of the FGF system and depression. These signaling molecules may be expected to be biomarkers for the diagnosis and prognosis of MDD, and may provide new drug targets for the treatment of depression. Here, we reviewed the correlation between some members of the FGF system and depression.

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Citations

Nov 5, 2019·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Jong Yung ParkKyung Ho Shin
Apr 24, 2020·Current Drug Targets·Fatemeh Forouzanfar, Hamid R Sadeghnia
Nov 24, 2020·Molecular Biology Reports·Ronald B Brown
Jan 15, 2021·Journal of Affective Disorders·Eli R LebowitzWendy K Silverman
Jul 1, 2020·Current Drug Targets·Ali TalaeiFatemeh Forouzanfar
Mar 23, 2021·Pharmacology & Therapeutics·Katarzyna MlyniecGabriel Nowak
Jun 25, 2021·Neurochemistry International·Si-Yu RenNai-Hong Chen

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Methods Mentioned

BETA
genotyping

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