Fibrous Dysplasia and Juvenile Psammomatoid Ossifying Fibroma: A Case of Mistaken Identity

The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-Craniofacial Association
Sergey Y TurinArun K Gosain

Abstract

Juvenile psammomatoid ossifying fibroma (JPOF) is a rare benign osseous tumor, usually presenting in the midface. There are many similarities in location, presentation, and radiographic appearance between fibrous dysplasia (FD) and JPOF. Awareness of this entity is important for craniofacial surgeons, as surgical timing and intraoperative management differ between these tumors. Findings that should raise suspicion of JPOF preoperatively include rapid growth, a shell of cortical bone surrounding the lesion, and clearly demarcated borders of the lesion on imaging, as opposed to a gradual transition between normal and abnormal bone. Definitive excision is the treatment of choice, and earlier surgery may provide better results by addressing the lesion at the smallest size possible. In contrast to FD, JPOF is not known to "burn out," so there is minimal benefit to be gained from delay. We present a summary of the evidence for diagnosis and treatment of JPOF as well our experience with JPOF in an 11-year-old female who was initially diagnosed with FD. We aim to draw attention to the similar presentations of these entities so the reader will be able to more accurately manage these patients.

References

Apr 1, 1991·Plastic and Reconstructive Surgery·Y R Chen, M S Noordhoff
Apr 1, 1990·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·P J Slootweg, H Müller
Jan 1, 1985·Ophthalmology·C E MargoD E Sweet
Oct 1, 1994·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·P J SlootwegP G Nikkels
Feb 24, 2001·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·P Ricalde, B B Horswell
Apr 6, 2001·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·R Leimola-VirtanenS Syrjänen
Apr 2, 2002·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Samir El-Mofty
Jun 1, 2002·The Journal of Craniofacial Surgery·Cuneyt OzekEcmel Songur
Jan 11, 2003·European Radiology·Nabil J KhouryMaurice C Haddad
Feb 3, 2009·Plastic and Reconstructive Surgery·Valentino ValentiniGiorgio Iannetti
Sep 1, 2007·Head and Neck Pathology·Robert D Foss, Christopher G Fielding
Jun 28, 2011·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Reiko NakajimaFumiko Kimura
Aug 16, 2011·Oral Oncology·Sachin C SarodeM Jashika
Jun 2, 2012·Journal of Maxillofacial and Oral Surgery·Suhail Amin Patigaroo
Jul 10, 2012·Oral and Maxillofacial Surgery Clinics of North America·Pat RicaldeJanice S Lee
Mar 1, 2010·Journal of Maxillofacial and Oral Surgery·Sondos Abuzinada, A Alyamani
Nov 21, 2015·Journal of Neurosurgery. Pediatrics·Cristina Barrena LópezEnrique Úrculo Bareño
Jan 8, 2016·International Journal of Oral and Maxillofacial Surgery·J HanL Xu
Jan 27, 2017·Acta Oto-laryngologica·Mingjie WangYunchuan Li

❮ Previous
Next ❯

Citations

Nov 6, 2020·Clinical and Experimental Otorhinolaryngology·Jung Joo LeeSeung-Kyu Chung

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy
surgical resection

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Head and Neck Pathology
Robert D Foss, Christopher G Fielding
JAMA Otolaryngology-- Head & Neck Surgery
Michael S HarrisMichael A Agostino
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Roman CarlosPablo Agustin Vargas
Clinical Nuclear Medicine
Rodrigo Cárdenas-PerillaJuan Manuel Muñoz-Acosta
© 2022 Meta ULC. All rights reserved