Fibrous hamartoma of infancy: an Italian multi-institutional experience

Journal of the American Academy of Dermatology
Elena CarrettoGiovanni Cecchetto

Abstract

Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. The clinical features and treatment results of 18 children with FH are described. Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery. The results did not reach statistical significance due to difficulties in collecting cases. FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.

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Citations

Feb 26, 2010·Skeletal Radiology·You Seon SongJong Woon Song
Dec 12, 2012·Journal of Lower Genital Tract Disease·Maryam MonajemzadehShanyandokht Taleb
May 11, 2012·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Cheryl M Coffin, Rita Alaggio
Jan 1, 2011·Indian Dermatology Online Journal·Rohan S VinayakPriti Trivedi
Feb 19, 2014·Skeletal Radiology·Seungsoo LeeMyoung Ju Koh
May 30, 2013·Indian Journal of Dermatology·Pilar F-Eire, Joaquin Gonzalez-Carrero Fojon
Feb 27, 2016·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Se Hyun ChoiNamju Kim
Jul 6, 2010·Journal of the American Academy of Dermatology·Joseph McGowanJoel Cook
Feb 11, 2015·Pediatric Dermatology·Laura MelnickJames R Treat
Feb 18, 2016·Journal of Pediatric and Adolescent Gynecology·Oranite GoldratJean-Christophe Noël
Nov 3, 2014·Ophthalmic Plastic and Reconstructive Surgery·Ann Q TranHeather D Potter
Nov 9, 2011·Journal of the Korean Surgical Society·Guhyun KangJeong Meen Seo
Jan 1, 2017·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Takuya OkusaMakoto Takeuchi
Jan 7, 2017·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Alyaa Al-IbraheemiAndrew L Folpe
Jan 18, 2020·Head and Neck Pathology·Esther Baranov, Jason L Hornick
Jan 1, 2021·Actas dermo-sifiliográficas·L Martos-CabreraM Llamas-Velasco
Jun 6, 2021·Actas dermo-sifiliográficas·L Martos-CabreraM Llamas-Velasco

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