Field trials of a vaccine against bovine mastitis. 2. Evaluation in two commercial dairy herds

Journal of Dairy Science
A CalzolariR Nagel

Abstract

A vaccine against bovine mastitis was developed. The vaccine was based on inactivated, highly encapsulated Staphylococcus aureus cells; a crude extract of Staph. aureus exopolysaccharides; and inactivated unencapsulated Staph. aureus and Streptococcus spp. cells. In this study, the vaccine was evaluated in 164 cows from two commercial dairies (A and B) during a 4-mo period. Two doses of the vaccine were administered subcutaneously to 82 cows in the brachiocephalicus muscle of the neck within a 4-wk interval. The results of this trial revealed significantly fewer intramammary infections caused by Staph. aureus at various levels of severity (clinical, subclinical, and latent) in cows that were vaccinated. The odds ratios of all types of intrammammary infections caused by Staph. aureus for dairies A and B, which were determined by a logistic model, were 1.84 and 1.89, respectively, for quarters of vaccinated cows and quarters of control cows. The colony counts for Staph. aureus in milk from infected quarters of vaccinated cows were significantly lower than those in milk from infected quarters of control cows. Also, the somatic cell counts per milliliter in milk from vaccinated cows were significantly decreased when the initial som...Continue Reading

References

Sep 1, 1978·The British Veterinary Journal·J C Anderson
Jan 1, 1992·Vaccine·D L Watson
Jan 1, 1989·Paediatric and Perinatal Epidemiology·T BjerkedalD W Hosmer
Mar 1, 1984·Journal of Dairy Science·K YoshidaW B Evans
May 1, 1997·Journal of Dairy Science·J A GiraudoR Nagel

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Citations

Feb 11, 2014·Pakistan Journal of Biological Sciences : PJBS·Rajib DebSushil Kumar
Jul 27, 2001·Journal of Veterinary Medicine. B, Infectious Diseases and Veterinary Public Health·M HoedemakerE Bleckmann
May 1, 1997·Journal of Dairy Science·J A GiraudoR Nagel
Oct 1, 2003·Veterinary Microbiology·Karin Jacobsson

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