PMID: 16537316Mar 16, 2006Paper

Fifteen years of experience in cholinesterase monitoring of insecticide applicators

Journal of Agromedicine
J E Lessenger

Abstract

Measuring cholinesterase(ChE) enzyme levels in red blood cells (RBC) and plasma has become a useful tool in the early detection of organophosphate and carbamate poisoning in insecticide handlers. Since 1974 the State of California has required testing of pesticide applicators to prevent disease. This study is a review of the testing experience of two physicians and using one laboratory so that a comparison can be made to previous studies by the author and others. The files of 366 workers who were referred by their employers for ChE activity monitoring were abstracted for patient data, employer identification, and testing data. Results were entered into the EPIINFO program for analysis. A total of 366 workers from 45 companies were tested over a 15-year period between 1989 and 2004. Most were applicators. There were 690 attempts to establish baselines, of which 545 (79%) were successful. There were 519 monitoring tests on 228 workers, resulting in the removal from exposure of 18 employees, most in 1996. Self-reported exposure history and symptoms resulted in only 3 responses (.6%). The costs were significant ($47,160 total and $36 per test), especially when considering the failure of 145 (21%) employees to establish baselines. T...Continue Reading

References

Jan 1, 1989·American Journal of Industrial Medicine·R G AmesR J Jackson
Aug 1, 1986·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·M J CoyeK T Maddy
Sep 7, 1999·The Journal of the American Board of Family Practice·J E Lessenger, B E Reese
Oct 25, 2002·International Journal of Toxicology·Barry W WilsonMichael A O'Malley

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Citations

Nov 22, 2011·Annals of Emergency Medicine·Bishan N RajapakseNicholas A Buckley
Aug 18, 2012·Chemico-biological Interactions·K Ofek, H Soreq
Sep 4, 2019·Rehabilitation Nursing : the Official Journal of the Association of Rehabilitation Nurses·Yovita Dwi SetiyowatiHsing-Mei Chen
Jun 9, 2017·Journal of Rural Medicine : JRM·Hiroshi NagamiMineko Nakazaki

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