Fighting Against Disuse of the Masticatory System in Duchenne Muscular Dystrophy: A Pilot Study Using Chewing Gum

Journal of Child Neurology
H Willemijn van BruggenStanimira I Kalaykova

Abstract

Duchenne muscular dystrophy patients report masticatory problems. The aim was to determine the efficacy of mastication training in Duchenne muscular dystrophy using chewing gum for 4 weeks. In all, 17 patients and 17 healthy age-matched males participated. The masticatory performance was assessed using a mixing ability test and measuring anterior bite force before, shortly after and 1 month after the training. In the patient group the masticatory performance improved and remained after 1-month follow-up, no significant changes in anterior maximum bite force was observed after mastication training. In the healthy subject the bite force increased and remained at the 1-month follow-up; no significant differences in masticatory performance were observed. Mastication training by using sugar-free chewing gum in Duchenne muscular dystrophy patients improved their masticatory performance. Since bite force did not improve, the working mechanism of the improvement in chewing may relate to changes of the neuromuscular function and coordination, resulting in improvement of skills in performing mastication.

References

Apr 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·Y KawazoeM Tamamoto
Sep 1, 1995·American Journal of Physical Medicine & Rehabilitation·C M McDonaldB J Sigford
Apr 1, 1995·American Journal of Orthodontics and Dentofacial Orthopedics : Official Publication of the American Association of Orthodontists, Its Constituent Societies, and the American Board of Orthodontics·S KiliaridisG E Carlsson
Nov 1, 1994·Archives of Physical Medicine and Rehabilitation·T N WilligJ Navarro
May 1, 1994·Journal of Oral Rehabilitation·A M Lobbezoo-ScholteF Bosman
Oct 1, 1993·Journal of Dental Research·A M Lobbezoo-ScholteF Bosman
Jun 22, 2002·Current Opinion in Genetics & Development·Madeleine Durbeej, Kevin P Campbell
Oct 24, 2002·Current Opinion in Clinical Nutrition and Metabolic Care·Amy Cameron, Jeffrey Rosenfeld
Mar 4, 2005·European Journal of Orthodontics·Tetsuya KamegaiDaisuke Inaba
Jun 22, 2005·Annals of Internal Medicine·Lisa HartlingTerry P Klassen
Aug 18, 2005·Neuromuscular Disorders : NMD·Carole BérardUNKNOWN MFM Collaborative Study Group
Oct 19, 2006·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·Marika PaneEugenio Mercuri
Dec 19, 2006·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Koichiro UekiEtsuhide Yamamoto
Dec 7, 2007·European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society·A AloysiusE Mercuri
Sep 23, 2008·Archives of Oral Biology·Sébastien BotteronStavros Kiliaridis
Sep 12, 2009·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·Z E Davidson, H Truby
Sep 18, 2009·European Journal of Oral Sciences·C M SpeksnijderA van der Bilt
Dec 1, 2009·Lancet Neurology·Katharine BushbyUNKNOWN DMD Care Considerations Working Group
May 22, 2010·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·A RioA Al-Chalabi
Jan 19, 2011·Journal of Oral Rehabilitation·Andries van der Bilt
Jul 26, 2011·International Journal of Paediatric Dentistry·Akira OhiraYuzo Takagi
Aug 18, 2012·Advances in Dental Research·P MilgromY Nakai
Dec 25, 2012·Journal of Neurology·Lenie van den Engel-HoekImelda J M de Groot
Mar 12, 2013·International Journal of Language & Communication Disorders·Sally K ArcherSimon Miller
May 15, 2013·Annals of Physical and Rehabilitation Medicine·A RapinF C Boyer
Nov 16, 2013·Annals of Physical and Rehabilitation Medicine·C VuillerotUNKNOWN Le groupe d’étude NM-Score
Jun 28, 2014·Neuromuscular Disorders : NMD·H W van BruggenS I Kalaykova

❮ Previous
Next ❯

Citations

Dec 10, 2016·Clinical Anatomy : Official Journal of the American Association of Clinical Anatomists & the British Association of Clinical Anatomists·Lenie Van Den Engel-HoekNens Van Alfen
Jun 7, 2017·Journal of Pediatric Rehabilitation Medicine·Lenie van den Engel-HoekHelen Cockerill
Jan 19, 2018·Journal of the Royal Society, Interface·Rachel Lev, Dror Seliktar
Mar 25, 2020·The American Journal of Occupational Therapy : Official Publication of the American Occupational Therapy Association·Evan Harry Lloyd MorrisSabrina W Yum
Nov 20, 2016·Journal of Neuromuscular Diseases·Lenie van den Engel-HoekCorrie E Erasmus
May 11, 2018·Clinical and Experimental Dental Research·Manami ShiraiEiji Tanaka
Apr 8, 2021·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Yutaka Fukumoto, Takeshi Miyama
Aug 29, 2021·Muscle & Nerve·Saskia L S Houwen-van OpstalImelda J M de Groot

❮ Previous
Next ❯

Methods Mentioned

BETA
force measurement

Software Mentioned

Adobe Photoshop
SPSS Statistics

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry
L Yu
Hiroshima Daigaku shigaku zasshi. The Journal of Hiroshima University Dental Society
M Kobayashi
Ryōikibetsu shōkōgun shirīzu
T Ishihara
© 2021 Meta ULC. All rights reserved