Film Self-Assembly of Oppositely Charged Macromolecules Triggered by Electrochemistry through a Morphogenic Approach

Langmuir : the ACS Journal of Surfaces and Colloids
A DochterF Boulmedais

Abstract

The development of new surface functionalization methods that are easy to use, versatile, and allow local deposition represents a real scientific challenge. Overcoming this challenge, we present here a one-pot process that consists in self-assembling, by electrochemistry on an electrode, films made of oppositely charged macromolecules. This method relies on a charge-shifting polyanion, dimethylmaleic-modified poly(allylamine) (PAHd), that undergoes hydrolysis at acidic pH, leading to an overall switching of its charge. When a mixture of the two polyanions, PAHd and poly(styrenesulfonate) (PSS), is placed in contact with an electrode, where the pH is decreased locally by electrochemistry, the transformation of PAHd into a polycation (PAH) leads to the continuous self-assembly of a nanometric PAH/PSS film by electrostatic interactions. The pH decrease is obtained by the electrochemical oxidation of hydroquinone, which produces protons locally over nanometric distances. Using a negatively charged enzyme, alkaline phosphatase (AP), instead of PSS, this one-pot process allows the creation of enzymatically active films. Under mild conditions, self-assembled PAH/AP films have an enzymatic activity which is adjustable simply by control...Continue Reading

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Citations

Feb 2, 2017·Langmuir : the ACS Journal of Surfaces and Colloids·Kazi SadmanKenneth R Shull
Apr 9, 2019·Journal of the Royal Society, Interface·Nikolay V RyzhkovEkaterina V Skorb
Jan 13, 2018·Physical Chemistry Chemical Physics : PCCP·Flavien SciortinoKatsuhiko Ariga
Oct 25, 2017·Angewandte Chemie·Jennifer Rodon ForesLoïc Jierry
Jun 28, 2019·Frontiers in Chemistry·Nikolay V RyzhkovEkaterina V Skorb
Sep 29, 2020·Advances in Colloid and Interface Science·Rebecca SikkemaIgor Zhitomirsky
Aug 2, 2017·ACS Applied Materials & Interfaces·Clément MaertenFouzia Boulmedais
Dec 15, 2016·Chemical Reviews·Joseph J RichardsonFrank Caruso

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