Financial Burden of Recurrent Urinary Tract Infections in Women: A Time-driven Activity-based Cost Analysis

Urology
Shivani GaitondePhilippe E Zimmern

Abstract

To utilize Time-Driven Activity-Based Costing to quantify costs of managing recurrent urinary tract infections (RUTI) in women. RUTI was defined as ≥2 UTIs in 6 months or ≥3 UTIs in 12 months. A care-delivery value chain outlined RUTI management (visits, urine studies, and imaging) for acute UTI followed by a form of long-term prevention. Prevention strategies included conservative therapy (Cranberry tablets, d-mannose, or lactobacillus); Estrogen therapy if postmenopausal; Antibiotic use (self-start, postcoital, or continuous regimens); or intravenous antibiotics in case of drug-resistance or intolerance. Costs of each resource were largely obtained from the Medicare Physician Fee Schedule, GoodRx and local pharmacy pricing, and institutional expenses. The capacity cost rate was defined as cost of resources per minute of care. Individual costs were summed to estimate overall expense of initial RUTI workup and annual cost for each long-term prevention strategy. Cost of acute RUTI workup ranged from $390 to $730. Acute antibiotics cost ranged from $10 for oral trimethoprim-sulfamethoxazole to $3970 for intravenous Ertapenem. Annually, mean cost of conservative therapy ranged from $50 for d-mannose to $1290 for vaginal estradiol ...Continue Reading

Citations

Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Christina M Coleman, Daneel Ferreira
Apr 15, 2021·International Urogynecology Journal·Baylie R HochstedlerLinda Brubaker
Apr 29, 2021·Female Pelvic Medicine & Reconstructive Surgery·Alexis A DieterUNKNOWN Developed by the AUGS Junior Faculty Research Network
May 12, 2021·Menopause : the Journal of the North American Menopause Society·Kate A FoxDavid D Rahn
Oct 12, 2021·Journal of Dietary Supplements·Roberto CotelleseStefano Togni
Jan 5, 2022·International Urogynecology Journal·Meghana Reddy, Philippe E Zimmern
Jan 28, 2022·Female Pelvic Medicine & Reconstructive Surgery·Timothy F CarrollPhilippe E Zimmern

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