Fine motor skills and interhemispheric transfer in treatment-naive male children with Tourette syndrome

Developmental Medicine and Child Neurology
Judith BuseVeit Roessner

Abstract

This study addressed whether Tourette syndrome is associated with an impairment of fine motor skills or altered interhemispheric transfer. We additionally investigated the association between interhemispheric transfer and size of the corpus callosum. The sample, a subsample of our larger neuroimaging sample, included 27 treatment-naive males with 'pure' Tourette syndrome (age range 10y 2mo-14y 4mo; mean age 11y 10mo, SD 1y 2mo) and 26 matched healthy comparison children (age range 10y 2mo-14y 4mo; mean age 11y 10mo, SD 1y 1mo). A finger tapping task and the Purdue Pegboard were used to assess fine motor skills. Interhemispheric transfer time (ITT) was measured with the Poffenberger paradigm. The neuroanatomical data were derived from our previous neuroimaging study. ITT was negatively correlated with the size of callosal subregion 3 (r=-0.366, p=0.028), indicating that a shorter ITT was associated with a larger corpus callosum. Our findings support the assumption that previously reported impairment of motor skills in Tourette syndrome does not directly result from tics but from other factors such as medication or comorbidities. Following the assumption that callosal subregion 3 in Tourette syndrome grows as a consequence of tic...Continue Reading

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Citations

May 10, 2012·Developmental Medicine and Child Neurology·Francisco Cardoso
Jun 19, 2012·Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie·Veit RoessnerAribert Rothenberger
Dec 15, 2012·Neuroscience and Biobehavioral Reviews·Christos GanosAlexander Münchau
Aug 17, 2014·Neuropsychologia·Christos GanosSimone Kühn
Aug 19, 2015·Journal of Experimental Neuroscience·Navkiran KalsiCarlo Lai
Jun 30, 2016·Journal of Developmental and Behavioral Pediatrics : JDBP·Erin R WallaceMatthew L Speltz
Jan 17, 2017·Cognitive Processing·Alexandros Tillas
May 14, 2019·Frontiers in Neurology·Davide MartinoLaura Avanzino
Aug 19, 2017·Brain Sciences·Simon Morand-BeaulieuBruno Gauthier
Mar 22, 2019·BioMed Research International·Francesca ValenteFrancesco Cardona
Nov 17, 2020·Frontiers in Neurology·Federica GraziolaAlessandro Capuano

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