Fine-Needle Aspiration Biopsy as a Preoperative Procedure in Patients with Malignancy in Solitary and Multiple Thyroid Nodules

PloS One
Krzysztof KaliszewskiTadeusz Łukieńczuk

Abstract

Fine-needle aspiration biopsy (FNAB) is a recognized technique for the basic, preoperative cytological diagnosis of thyroid nodules. To analyze the accuracy of FNAB in the diagnosis of thyroid cancer in patients with solitary and multiple thyroid nodules and to compare the demographic, clinical and pathological characteristics of patients with thyroid carcinoma in solitary and multiple tumors. The case records of 2,403 patients with solitary and multiple thyroid tumors treated consecutively between 2008 and 2013 were analyzed retrospectively. We selected 1,645 for further analysis. A solitary thyroid nodule was observed in 493 patients, and multiple nodules were detected in 1,152 patients. Further classification of the patients in these two groups was performed on the basis of the FNAB results, type of surgery performed and histopathology. TC was histopathologically confirmed in 166 patients, and benign disease was found in 1,479. The TC patients were assigned to the study group, and those with benign thyroid disease were placed into the control group. The study group was divided into two subgroups according to the presence of cancer in a single thyroid nodule or in multiple nodules. Malignancy in a solitary thyroid nodule was ...Continue Reading

References

Sep 1, 1983·Journal of Clinical Pathology·K C Suen, N F Quenville
Nov 1, 1994·The American Journal of Medicine·E L Mazzaferri, S M Jhiang
Dec 17, 1994·Lancet·M KondeS Diallo
Dec 1, 1993·Acta Endocrinologica·F Aghini-LombardiP Vitti
Jun 12, 1998·Thyroid : Official Journal of the American Thyroid Association·R M TuttleH B Burch
Apr 25, 2000·Thyroid : Official Journal of the American Thyroid Association·S R TollinS Perlmutter
Mar 20, 2001·Archives of Surgery·E KoikeH Yamashita
Feb 22, 2002·AJR. American Journal of Roentgenology·Eun-Kyung KimHyung Sik Yoo
May 8, 2002·The Journal of Clinical Endocrinology and Metabolism·Enrico PapiniClaudio M Pacella
May 18, 2004·The Surgical Clinics of North America·M Sean Boger, Nancy D Perrier
Jun 24, 2006·European Journal of Endocrinology·Carlo CappelliEnrico Agabiti Rosei
Jan 9, 2007·Journal of Clinical Ultrasound : JCU·Dragica Obad KovacevicMirna Smetana Skurla
Feb 16, 2008·Internal Medicine·Serdal UgurluPinar Kadioglu
Apr 12, 2008·Radiology·Won-Jin MoonUNKNOWN Thyroid Study Group, Korean Society of Neuro- and Head and Neck Radiology
Apr 21, 2009·European Journal of Endocrinology·Bozena PopowiczDorota Słowińska-Klencka
Nov 16, 2010·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Oktay AlginErcan Tuncel
May 7, 2011·American Journal of Surgery·Thomas W T HoAdrian Harvey
Mar 16, 2013·The Journal of Surgical Research·Nicholas CooroughHerbert Chen
Jul 11, 2013·Thyroid : Official Journal of the American Thyroid Association·Markus EszlingerRalf Paschke
Jan 2, 2015·Turkish Journal of Medical Sciences·Ali Erkan UçarAbdussamed Yalçin

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Methods Mentioned

BETA
biopsy
total resection

Software Mentioned

STATISTICA
MedCalc

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