PMID: 7544720Jun 1, 1995Paper

Fine-needle aspiration cytology of seminoma: a review of 16 cases

Diagnostic Cytopathology
N P CarawayN Sneige

Abstract

We report the cytomorphologic features of 16 fine-needle aspiration (FNA) biopsies of seminoma obtained from 16 male patients. The aspirates included two primary gonadal tumors (one occurring in a cryptorchid testis), two primary mediastinal tumors, and 12 metastases (two with unknown primaries). Analysis of the aspirates revealed a primarily dispersed cell population of large cells with scant to moderately abundant cytoplasm. The nuclei were round to slightly irregular, had finely granular chromatin, and had either one central prominent nucleolus or two to three smaller nucleoli. Variable numbers of lymphocytes and plasma cells were intermingled with the tumor cells. Only a few cases had epithelioid histiocytes or the characteristic "tigroid" background. The cytologic features of the metastases were distinctive and were considered diagnostic for therapeutic management. In six cases, an initial diagnosis of seminoma by FNA biopsy identified the neoplasm as germ cell in origin rather than other neoplasms in the differential diagnosis, thereby expediting therapeutic management.

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Citations

Jun 1, 1996·Diagnostic Cytopathology·R S HodaV E Reuter
Jan 1, 1997·Diagnostic Cytopathology·M Akhtar, F al Dayel
Nov 14, 2000·Diagnostic Cytopathology·A AssiL Cozzi
Apr 12, 2002·Journal of Clinical Ultrasound : JCU·Costanza BrunoCarlo Procacci
Aug 26, 1998·Cytopathology : Official Journal of the British Society for Clinical Cytology·J García-SolanoM Pérez-Guillermo
Sep 1, 2011·Journal of Avian Medicine and Surgery·Ahmad SaiedNobuko Wakamatsu
May 10, 2011·Journal of Cytology·Abhishant PandeyGv Manjunath
Dec 31, 2015·Diagnostic Cytopathology·Chang-Tsu Yuan, Min-Shu Hsieh
Sep 11, 2002·American Journal of Clinical Pathology·David C ChhiengAylin Simsir
Sep 6, 2008·Diagnostic Cytopathology·Mariam AlsharifStefan E Pambuccian
Feb 3, 2012·Diagnostic Cytopathology·Nozomi IwamotoHidetoshi Okabe
Nov 21, 2009·Diagnostic Cytopathology·Swathi Eluri, Syed Z Ali
Jan 15, 2010·Diagnostic Cytopathology·Yoshiki OhtaHidekazu Ota
Feb 22, 2014·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·J JavanbakhtR Emrani Bidi
May 24, 2017·Tropical Doctor·Uma HandaVidur Bhalla
Aug 20, 2005·Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine·C MasserdottiO Zanetti
Apr 23, 2014·Cytopathology : Official Journal of the British Society for Clinical Cytology·I CozzolinoP Zeppa
Jul 16, 2015·Diagnostic Cytopathology·Surbhi GoyalPreeti Diwaker
Mar 15, 2011·Biotechnic & Histochemistry : Official Publication of the Biological Stain Commission·K P Krafts, S E Pambuccian
Apr 10, 2003·Archives of Pathology & Laboratory Medicine·Anil V Parwani, Syed Z Ali

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