Fine needle aspiration of thyroid nodules in the pediatric population: a 12-year cyto-histological correlation experience at North Shore-Long Island Jewish Health System

Diagnostic Cytopathology
Seema A LalePatricia G Wasserman

Abstract

Diagnostic evaluation of thyroid nodules by FNA is used in the clinical management triage based on the knowledge of the rate of malignancy of each diagnostic category. The Bethesda System for Reporting Thyroid Cytopathology was published in 2007 by the National Cancer Institute (NCI). Using this classification, we studied our institution's experience in the pediatric population calculating the rate of malignancy for each diagnostic category, comparing our findings to our general patient population and that of the literature. 13,312 thyroid FNAs were performed at our institution between 1998 and 2010. 282 cases were from patients under 19 years of age. We reviewed and reclassified these cases using the new NCI categories, and pursued cytology-surgical follow-up. Of the 282 FNA cases, 20.92% (59) were classified as unsatisfactory (U), 48.22, % (136) benign (B), 2.12% (6) Atypia of undetermined significance (AUS), 14.18% (40) suspicious for follicular neoplasm (FN), 2.12% (6) suspicious for malignancy (SM) and 12.41% (35) positive for malignancy (P). The U-category was further classified into nondiagnostic (ND) 12.41% (35) and cysts (C) 8.51% (24). Seventy-four children had surgical follow-up. The rates of histologically confirmed...Continue Reading

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Citations

Feb 16, 2012·International Journal of Pediatric Otorhinolaryngology·Francesca FoltranDario Gregori
Mar 13, 2016·Cancer Cytopathology·Kristen L PartykaHoward H Wu
Jul 15, 2016·Cancer Cytopathology·Elmira AmirazodiJonathan D Wasserman
Mar 10, 2016·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Phillip HuyettJeffrey P Simons
Feb 16, 2019·Cancer Cytopathology·Huiying WangVivian L Weiss
Jun 30, 2019·Diagnostic Cytopathology·Amer HeiderXin Jing
Jul 13, 2019·Thyroid : Official Journal of the American Thyroid Association·Christine E CherellaAri J Wassner
Jul 31, 2019·Current Opinion in Endocrinology, Diabetes, and Obesity·Andrew J Bauer
Apr 8, 2018·Diagnostic Cytopathology·Priya PathakSonal Sharma
Dec 4, 2020·American Journal of Clinical Pathology·Huy Gia VuongAndrey Bychkov
Jan 29, 2021·Thyroid : Official Journal of the American Thyroid Association·Huy Gia VuongAndrey Bychkov
Feb 26, 2021·Journal of Pediatric Endocrinology & Metabolism : JPEM·Wen JiangRon S Newfield

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