Fine-needle biopsy of hamartomas of the lung

AJR. American Journal of Roentgenology
W N Sinner

Abstract

Hamartomas are unexpectedly detected in asymptomatic patients, in mass surveys, general health examinations, and chest radiographs for other reasons. They often present a difficult problem both for the radiologist and the referring clinician, as their differentiation from lung carcinoma or a metastasis may be impossible by radiography. Although the typical radiographic appearance of a well circumscribed, solitary, lobulated nodule smaller than 4 cm in diameter with popcorn calcification permits confident recognition, most hamartomas present as noncharacteristic nodules. Some authors, therefore, recommend thoracotomy for a definitive diagnosis. Needle biopsy was helpful in this study for diagnosis in 61 cases. In 42 cases, one procedure requiring two or three punctures was sufficient to obtain the diagnosis; in 17, two procedures (one to three punctures) were required; and in two, three procedures were necessary. Of 61 cases, surgery was performed in 20. The histology of the surgical specimen confirmed the diagnosis except in two cases, in which a benign fibroma and a benign chemodectoma were found. The 5 year follow-up of the 41 cases not operated on showed no evidence of malignancy.

Citations

Jan 1, 1997·Surgery Today·Y OtaniY Morishita
Jul 1, 1988·Postgraduate Medical Journal·R Dick
Oct 31, 2003·Thorax·A ManhireUNKNOWN BTS
Jan 18, 2013·Journal of Cytology·T UmashankarParasappa J Yaranal
Jan 1, 1993·The British Journal of Radiology·W Burke, M B Rubens
Sep 1, 1989·Chest·F CloreJ Saterfiel
Mar 29, 2007·Cytopathology : Official Journal of the British Society for Clinical Cytology·A SaqiM F Vazquez
Jul 1, 1984·The Journal of Computed Tomography·D G VarmaP Moulder
Sep 28, 2015·Interactive Cardiovascular and Thoracic Surgery·Hany ElsayedSalma E Elbastawisy
Jun 1, 1984·Chest·W N Sinner
Oct 9, 2004·Cognitive Behaviour Therapy·Nina HeinrichsDavid H Barlow
Jul 1, 2005·Cognitive Neuropsychology·Martin Arguin, Daniel Bub
Jan 1, 1987·Journal of Sex & Marital Therapy·B J JensenL R Upton
Apr 17, 2009·The Clinical Neuropsychologist·Catherine C PriceDavid J Libon
Jan 5, 2005·Archives of Pathology & Laboratory Medicine·Jonathan H HughesUNKNOWN Cytopathology Resource Committee, College of American Pathologists

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.