Fine particulate matter and incidence of metabolic syndrome in non-CVD patients: A nationwide population-based cohort study

International Journal of Hygiene and Environmental Health
Seulbi LeeEunhee Ha

Abstract

It has been reported that particulate matter (PM) is associated with cardiovascular diseases (CVD) while metabolic syndrome is also an important risk factor for CVD. However, few studies have investigated the epidemiological association between PM and metabolic syndrome. To investigate the association between one-year exposure to PM with an aerodynamic diameter <2.5 μm (PM2.5) and the risk of metabolic syndrome in Korean adults without CVD. Exposure to PM2.5 was assessed using a Community Multiscale Air Quality (CMAQ) model. Metabolic syndrome was defined by National Cholesterol Education Program Adult Treatment Panel III. Andersen and Gill model with time-varying covariates, considering recurrent events, was used to investigate the association between one-year average PM2.5 and the risk of incident metabolic syndrome in 119,998 adults from the national health screening cohort provided by Korea National Health Insurance from 2009 to 2013. Higher risk of metabolic syndrome, waist-based obesity, hypertension, hypertriglyceridemia, low HDL cholesterol, and hyperglycemia were significantly associated with a 10-μg/m3 increase in PM2.5 [adjusted hazard ratio (HR): 1.070, 1.510, 1.499, 1.468, 1.627 and 1.380, respectively]. In additio...Continue Reading

Citations

Sep 15, 2019·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Caleb E Finch, Alexander M Kulminski
Apr 30, 2020·Environmental Health Perspectives·Dana Boyd BarrUNKNOWN (HAPIN Investigative Team)
Aug 6, 2020·Particle and Fibre Toxicology·Siri A N HolmeGitte Juel Holst
Jan 21, 2021·Experimental Biology and Medicine·Lisa Kobos, Jonathan Shannahan
Jun 14, 2021·The Science of the Total Environment·Nguyen Thanh TungHsiao-Chi Chuang
Jul 16, 2021·Environmental Research·Si-Tian ZangYu-Hong Zhao

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