Fine-scale temperature fluctuation and modulation of Dirofilaria immitis larval development in Aedes aegypti

Veterinary Parasitology
Nicholas Ledesma, Laura Harrington

Abstract

We evaluated degree-day predictions of Dirofilaria immitis development (HDU) under constant and fluctuating temperature treatments of equal average daily temperature. Aedes aegypti mosquitoes were infected with D. immitis microfilariae and parasite development was recorded at set time points in dissected mosquitoes. Time to L3 development in Malpighian tubules and detection in mosquito heads was shorter for larvae experiencing a daily regime of 19±9°C than larvae at constant 19°C; larval development rate in Malpighian tubules was slower in fluctuating regimes maintained above the 14°C developmental threshold than larvae under constant temperatures. We showed that hourly temperature modeling more accurately predicted D. immitis development to infective L3 stage. Development time differed between fluctuating and constant temperature treatments spanning the 14°C development threshold, implicating a physiological basis for these discrepancies. We conclude that average daily temperature models underestimate L3 development-and consequently dog heartworm transmission risk-at colder temperatures, and spatiotemporal models of D. immitis transmission risk should use hourly temperature data when analyzing high daily temperature ranges spa...Continue Reading

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Dec 14, 2011·Topics in Companion Animal Medicine·Nicholas Ledesma, Laura Harrington

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Citations

Nov 12, 2017·Parasites & Vectors·Risto PietikäinenAntti Oksanen
Jul 18, 2017·PloS One·Fernando Jose AntonioRenio Dos Santos Mendes
Nov 7, 2019·Journal of Medical Entomology·Meredith R Spence Beaulieu, Michael H Reiskind
Feb 22, 2017·Parasites & Vectors·Cornelia SilaghiAlexander Mathis
Dec 11, 2020·Environmental Pollution·Erik Neff, Guha Dharmarajan
May 6, 2021·Journal of the Royal Society, Interface·Calistus N NgonghalaMatthew H Bonds
Sep 11, 2021·Parasites & Vectors·Katherine E L Worsley-TonksMeggan E Craft

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