Fine structure and invasive behaviour of the early developmental stages of Theileria annulata in vitro

Veterinary Parasitology
W G JuraB Kelly

Abstract

The interaction, in vitro, between bovine peripheral blood lymphocytes and sporozoites of Theileria annulata (Ankara) was studied by light and electron microscopy. Beginning five minutes following incubation, samples were taken for Giemsa-stained smears and glutaraldehyde-fixed pellets, for light and electron microscopy, respectively. Sporozoites of T. annulata measure an average of 0.9 microns long, 0.8 microns broad and possess a limiting unit membrane, the pellicle; a round-to-ovoid, eccentrically situated, non-chromocentric nucleus; double-membraned, tubular, acristate mitochondria; varying numbers of anisocytic, densely osmiophilic and pleomorphic organelles, the rhoptries which together with the polar ring form the apical complex; and numerous, loosely scattered, electron-dense ribosomal particles. As early as 5 min of incubation, sporozoites had made contact with, and penetrated, lymphocytes. Sporozoites consistently attached to the lymphocyte plasmalemma by their basal end, possibly at specific receptor sites. Apparently only a proportion of lymphocytes (up to 40% and more commonly 10-20%) were susceptible. Two subpopulations of the susceptible lymphocytes were observed; one which appeared to have receptor sites localiz...Continue Reading

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Citations

May 15, 1989·Molecular and Biochemical Parasitology·B ShielsA Tait
Apr 1, 1990·Molecular and Biochemical Parasitology·J GlascodineB Shiels
Jul 1, 1992·Molecular and Biochemical Parasitology·R HallA Tait
May 1, 1997·International Journal for Parasitology·M K Shaw
Aug 21, 2008·Current Neurology and Neuroscience Reports·Karl C Golnik

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