Fine structures of the basophil infiltration in regional lymph nodes of the guinea-pig after the intradermal injection of T cell mitogens

Experientia
M Kimura, K Takaya

Abstract

Basophil-rich infiltrates in regional lymph nodes of guinea-pigs were demonstrated by electron microscopy after the intradermal injection of T cell mitogens (PHA and Con A). Basophils infiltrated the stroma of the lymph node via the postcapillary venules (PCV) and migrated to the paracortex. Prior to infiltration of the lymph nodes a cutaneous basophil hypersensitivity reaction was seen in the mitogen-injected skin. B cell mitogen (LPS) injection did not induce this response.

References

Jan 1, 1975·International Archives of Allergy and Applied Immunology·R H Kelly
Jan 1, 1979·International Archives of Allergy and Applied Immunology·M Kimura, K Takaya
Sep 1, 1970·The Journal of Experimental Medicine·H F DvorakM J Karnovsky
Jan 1, 1980·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·A O Myking

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