Finger drop sign-Characteristic pattern of distal weakness in Guillain-Barré Syndrome: A case report and review of the literature

SAGE Open Medical Case Reports
Yong Chuan Chee, Beng Hooi Ong

Abstract

Guillain-Barré Syndrome is an acquired acute autoimmune polyradiculoneuropathy that commonly presents with limb weakness and occasional cranial nerve, respiratory and autonomic involvement. Although the classic description of Guillain-Barré Syndrome is that of a demyelinating neuropathy with ascending weakness, predominant bilateral finger drop as presenting feature has rarely been reported. A characteristic pattern of weakness involving the extensor components of the fingers known as "finger drop sign" has been first described to be specific in acute motor axonal neuropathy form of Guillain-Barré Syndrome in the literature. We report a case of acute motor-sensory axonal neuropathy, which showed characteristic pattern of predominant finger extensor weakness, and provide a summary of all reported cases to date. While previous reports suggested that this is a sign that carries good prognosis, our case report suggested otherwise as the patient succumbed to respiratory and autonomic complications. Further studies are needed to evaluate the clinical significance of this peculiar sign.

References

Apr 15, 2009·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·G GalassiM Odaka
Jul 10, 2009·Neurology India·Arun GeorgeJose James
Nov 26, 2009·Neurology India·Vimal K Paliwal, Goel Gaurav
Jun 15, 2012·The New England Journal of Medicine·Nobuhiro Yuki, Hans-Peter Hartung
Aug 10, 2013·Journal of the Neurological Sciences·Georgios TsivgoulisCharitomeni Piperidou
Oct 29, 2013·Brain : a Journal of Neurology·Christiaan FokkeBart Casper Jacobs
Sep 2, 2015·Brain & Development·Rachana DubeySheffali Gulati

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