Fingernail may not be a reliable biomarker of fluoride body burden from dentifrice

Brazilian Dental Journal
Ynara Bosco Oliveira Lima-ArsatiJ A Cury

Abstract

Fingernail has been suggested as a biomarker of fluoride (F) body burden, but there is no consensus if it would be a reliable indicator of F exposure from dentifrice. Therefore, the present study was conducted to investigate if fingernails would have sensitivity to detect F exposure from dentifrice in young children. Twenty-three 1-3-year-old children living in the city of Piracicaba (0.72 ppm F in water), Brazil, were enrolled in two phases of different F exposure: in phase A (1st to 11th week), they were exposed to the combination of F from diet (solids and liquids) and dentifrice (1,500 microg F/g as MFP), and in phase B (12th to 29th week), only to F from diet (the use of F dentifrice was interrupted). Fingernails were weekly clipped during 35 weeks for F determination. F intake from diet and dentifrice in each phase was also determined. Both analyses were made with ion-specific electrode. F intake (Mean +/- SD) was significantly higher (p<0.01) when the children were exposed to F from diet+dentifrice than only to F from diet (0.086 +/- 0.032 and 0.040 +/- 0.009 mg F/day/kg body weight, respectively). However, F concentrations in nails collected during the whole experimental period of 35 weeks presented great variation with...Continue Reading

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Mar 31, 2005·Brazilian Dental Journal·Jaime Aparecido CuryAdriana Franco Paes Leme
Nov 24, 2005·Journal of Dental Research·J A CuryP L Rosalen
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Citations

Jul 22, 2011·International Journal of Environmental Research and Public Health·Carolina C MartinsJaime A Cury
Mar 29, 2014·Community Dentistry and Oral Epidemiology·Jackeline G AmaralAlberto C B Delbem
Dec 5, 2012·Brazilian Dental Journal·Suzely Adas Saliba MoimazNemre Adas Saliba
Dec 6, 2018·Brazilian Dental Journal·Emerson Tavares de SousaFábio Correia Sampaio
Jan 8, 2021·International Journal of Environmental Research and Public Health·Jesús Lavalle-CarrascoRonell Bologna-Molina
Jan 22, 2020·Caries Research·Oladipo S IdowuFatemeh Vida Zohoori
Jun 2, 2021·Caries Research·Oladipo S IdowuFatemeh V Zohoori

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