First efficacy and safety study of femtosecond lenticule extraction for the correction of myopia: six-month results

Journal of Cataract and Refractive Surgery
W SekundoM Blum

Abstract

To prospectively study the feasibility of femtosecond lenticule extraction (FLE), a new method of refractive correction. Department of Ophthalmology, Philipps University of Marburg and Helios Clinic, Erfurt, Germany. A flap and a lenticule of intrastromal corneal tissue were simultaneously cut with a VisuMax femtosecond laser system. Next, the lenticule was manually removed and the flap repositioned. The target refraction in all cases was -0.75 diopter (D). All 10 myopic eyes in the initial treatment group completed the final 6-month follow-up. The mean patient age was 39 years. The mean spherical equivalent (SE) was -4.73 +/- 1.48 (SD) preoperatively and -0.33 +/- 0.61 D 6 months postoperatively. Ninety percent of eyes were within +/-1.00 D and 40% were within +/-0.50 D of the intended correction. No eye lost 2 or more Snellen lines. Corneal topography showed large, prolate optical zones. Aberrometry showed no significant induction of higher-order aberrations. On a standardized questionnaire, all patients said they were very satisfied with the results. Preliminary results indicate that FLEx [corrected] is a promising new corneal refractive procedure to correct myopia.

Associated Clinical Trials

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Citations

Aug 10, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·M Blum, W Sekundo
Jun 15, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marcus BlumWalter Sekundo
Dec 6, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jana GertnereWalter Sekundo
Jun 25, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Anders H VestergaardJesper Ø Hjortdal
Dec 15, 2010·Current Opinion in Ophthalmology·Ramon Naranjo-Tackman
Jul 9, 2010·International Ophthalmology Clinics·Mohamed Abou Shousha, Sonia H Yoo
Jul 12, 2013·The British Journal of Ophthalmology·Jose L Güell
Feb 12, 2011·Ophthalmic Research·Jens HeichelKathleen S Kunert
Jun 15, 2013·Clinical Ophthalmology·Ahmet DemirokOmer Faruk Yilmaz
Mar 22, 2014·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Walter SekundoIgor Solomatin
Jun 20, 2014·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T Seiler
May 27, 2014·Journal of Cataract and Refractive Surgery·Abhijit Sinha RoyCynthia J Roberts
Apr 1, 2014·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·Alper AğcaOmer F Yilmaz
Dec 4, 2014·Journal of Cataract and Refractive Surgery·Chee Wai WongJodhbir S Mehta
Feb 5, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Marcus BlumWalter Sekundo
Jan 18, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kathleen S KunertJens Heichel
Dec 3, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Zhen-Yong Zhang, Matthew R Hoffman
Jan 3, 2013·Expert Review of Medical Devices·Kemal OzulkenSonia H Yoo
Feb 13, 2016·Lasers in Medical Science·Walter SekundoMarcus Blum
Feb 11, 2016·Current Eye Research·Shengsheng WeiXiaolian Su
Feb 1, 2014·Journal of Cataract and Refractive Surgery·Anders H VestergaardJesper Ø Hjortdal
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May 22, 2013·Journal of Cataract and Refractive Surgery·Zixian Dong, Xingtao Zhou
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Sep 18, 2012·Journal of Cataract and Refractive Surgery·Anders VestergaardJesper Ø Hjortdal
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Dec 13, 2012·Journal of Refractive Surgery·George D KymionisDan Z Reinstein

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