First genome sequence of St. Louis encephalitis virus (SLEV) isolated from a human in Brazil

Archives of Virology
Danila VedovelloMaurício Lacerda Nogueira

Abstract

St. Louis encephalitis virus (SLEV), a member of the family Flaviviridae, genus Flavivirus, is a causative agent of encephalitis in the Americas. In Brazil, sporadic cases of SLEV infection have been reported since 1953, but the first outbreak of SLEV in Brazil was identified only in 2007, concomitant with an outbreak of dengue virus (DENV) serotype 3. This finding, along with other reports, indicates that SLEV circulation in Brazil is largely unknown, and there may be epidemiological implications of the co-circulation of SLEV, DENV and other flaviviruses in Brazil. Here, we describe the first complete genome sequence of an SLEV strain isolated from a human patient in Brazil, strain BeH 355964. Phylogenetic analysis was performed to determine the genotype of BeH 355964 using the full-length genome and envelope (E) gene sequences separately. Both analyses showed that BeH 355964 could be classified as genotype V. Although the number of single gene sequences available is greater (such as for the E gene), the phylogenetic tree based on the complete genome sequence was better supported and provided further information about the virus.

References

Nov 1, 1987·The American Journal of Tropical Medicine and Hygiene·T P Monath, T F Tsai
Jan 1, 1969·Annual Review of Medicine·J P LubyJ P Sanford
Sep 1, 1980·The American Journal of Tropical Medicine and Hygiene·T P MonathJ J Gardner
Jan 1, 1981·The American Journal of Tropical Medicine and Hygiene·F P PinheiroO F Leite
Nov 1, 1980·The American Journal of Tropical Medicine and Hygiene·G S BowenL J Kirk
Jul 25, 2000·Emerging Infectious Diseases·J H RappoleZ Hubálek
Dec 13, 2000·Microbes and Infection·L T Figueiredo
Jan 17, 2002·Viral Immunology·K A Bernard, L D Kramer
Jan 29, 2002·Archives of Virology·L D Kramer, L J Chandler
Jun 6, 2002·Revista Do Instituto De Medicina Tropical De São Paulo·Lorena Ivana SpinsantiMarta Silvia Contigiani
Jan 1, 1958·The American Journal of Tropical Medicine and Hygiene·O R CAUSEY, M THEILER
Feb 8, 2005·Journal of Clinical Microbiology·Roberta Vieira de Morais BronzoniLuiz Tadeu Moraes Figueiredo
Nov 23, 2005·Revista Do Instituto De Medicina Tropical De São Paulo·Iray M RoccoAkemi Suzuki
May 16, 2006·Memórias do Instituto Oswaldo Cruz·Cecília Luiza Simões dos SantosIray Maria Rocco
Mar 21, 2007·Emerging Infectious Diseases·Adriano MondiniMaurício Lacerda Nogueira
Mar 21, 2007·Emerging Infectious Diseases·Jens LindbergTeun Boekhout
Apr 1, 2008·Molecular Phylogenetics and Evolution·Gregory J BaillieSusan L Perkins
Jul 18, 2008·The Journal of General Virology·Fiona J MayAlan D T Barrett
Aug 19, 2008·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Albert J AugusteChristine V F Carrington
Apr 1, 2009·Emerging Infectious Diseases·Christy L OttendorferLillian M Stark
Jul 2, 2010·The Journal of General Virology·Sueli G RodriguesPedro F C Vasconcelos
Jul 22, 2010·Vector Borne and Zoonotic Diseases·Ana Carolina Bernardes TerzianMaurício Lacerda Nogueira
May 23, 2012·Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology·Laura E ValinottoAlicia S Mistchenko
Aug 29, 2012·Comparative Immunology, Microbiology and Infectious Diseases·Niranjan MishraScott H Newman
Jun 14, 2013·MBio·Anne KoppSandra Junglen
Oct 18, 2013·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Nov 28, 2013·PLoS Neglected Tropical Diseases·Roberta RosaRenato Lima Santos
Jan 31, 2014·Western Pacific Surveillance and Response Journal : WPSAR·Daniel TompkinsGraham Mackereth
Mar 25, 2014·Emerging Infectious Diseases·Vidal FelicesEric S Halsey

❮ Previous
Next ❯

Citations

Mar 19, 2016·Vector Borne and Zoonotic Diseases·Pedro F C Vasconcelos, Charles H Calisher
Mar 24, 2017·Journal of Neuroinflammation·Rafael Elias MarquesMauro M Teixeira
Dec 21, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Sabrina Ribeiro SantanaTamara Nunes Lima-Camara
May 31, 2018·PLoS Neglected Tropical Diseases·Tauyne Menegaldo PinheiroMaurício Lacerda Nogueira
Oct 20, 2021·Journal of Medical Virology·Marília M MoraesAdriano Mondini

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.