First-in-Man Transcervical Surgical Aortic Valve Replacement Using the CoreVista System

Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery
Otto E DapuntFraser W H Sutherland

Abstract

This study aimed to evaluate a novel device system for surgical aortic valve replacement (SAVR) using a unique new less invasive access approach. The hypothesis is that SAVR can be performed through a short transverse incision in the neck, similar to that used for transcervical thymectomy avoiding chest disruption. A new device system was developed to provide retraction, step-by-step illumination, and on-screen visualization for the new approach. Preliminary feasibility studies were performed in cadavers. Comprehensive risk analysis was performed, and training was implemented in Thiel preserved cadavers. For the first-in-man clinical case, a 63-year-old woman with symptomatic critical aortic stenosis (The Society of Thoracic Surgeons risk, 11%) and heavily calcified aortic valve was selected. A short transverse incision was made in the neck; the device was introduced, and the sternum was elevated; femorofemoral cardiopulmonary bypass was established; substernal dissection was guided by the sequenced illumination, and high-definition visualization was provided by the device, allowing for optimal exposition of the aorta and aortic valve; and a 23-mm Medtronic ENABLE sutureless valve prosthesis was implanted. Procedure success was...Continue Reading

References

Mar 1, 1988·The Annals of Thoracic Surgery·J D CooperH E Humphrey
Aug 1, 1996·The Annals of Thoracic Surgery·D M Cosgrove, J F Sabik
May 16, 1998·The Annals of Thoracic Surgery·S R GundryL L Bailey
Dec 29, 1999·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·E A GrossiA C Galloway
Feb 24, 2001·Journal of Cardiac Surgery·J G ByrneL H Cohn
Sep 22, 2001·The Annals of Thoracic Surgery·P SchroeyersH Vanermen
Aug 14, 2002·The Annals of Thoracic Surgery·Joseph B ShragerLarry R Kaiser
Oct 30, 2003·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Marc de PerrotShaf Keshavjee
Mar 26, 2005·Surgical Endoscopy·J BramisE Bastounis
Jul 13, 2005·Acta Neurologica Scandinavica·C-S HuangM-H Huang
Oct 26, 2006·The Annals of Thoracic Surgery·Joseph B ShragerLarry R Kaiser
Feb 23, 2008·The Annals of Thoracic Surgery·Bari MurtuzaThanos Athanasiou
Mar 5, 2009·The Journal of Thoracic and Cardiovascular Surgery·Morgan L BrownHartzell V Schaff
May 25, 2010·The Annals of Thoracic Surgery·Joseph B Shrager
Dec 31, 2010·Langenbeck's Archives of Surgery·Luca AmpolliniPaolo Carbognani
Jun 17, 2011·The Heart Surgery Forum·Raja R GopaldasDenton A Cooley
Jul 5, 2011·The Journal of Thoracic and Cardiovascular Surgery·Mattia GlauberPier A Farneti
Feb 10, 2012·Current Opinion in Cardiology·Konstantinos ZannisFrançois Laborde
Mar 13, 2012·The Journal of Thoracic and Cardiovascular Surgery·Thorsten DrewsAxel Unbehaun
Feb 5, 2013·Journal of the American College of Cardiology·Philippe GénéreuxMartin B Leon
Feb 26, 2013·Journal of the American College of Cardiology·David A RoyStephen J Brecker
Aug 27, 2013·The Annals of Thoracic Surgery·Vinod H ThouraniVasilis Babaliaros
Jul 30, 2014·The Annals of Thoracic Surgery·Kevin PhanTristan D Yan
Sep 27, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Norman MangnerAxel Linke
Dec 3, 2014·Trends in Cardiovascular Medicine·Mohamed Abdel-WahabGert Richardt
Dec 3, 2014·The Journal of Thoracic and Cardiovascular Surgery·Eduard PermanyerRafael Llorens

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Citations

Jul 29, 2021·JTCVS Techniques·Fraser William Havern SutherlandPhilip Curry

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