PMID: 2092364Nov 1, 1990Paper

First isolation of bacteriophages for a spirochaete: potential genetic tools for Leptospira

Research in Microbiology
Isabelle Saint GironsG Baranton

Abstract

Three bacteriophages of the saprophytic aquicole bacterium Leptospira biflexa were isolated from sewage waters from the outskirts of Paris, France. These phages do not infect representative strains of the pathogenic species Leptospira interrogans, and their host range is restricted to serovar patoc of the saprophytic species. The phages were found to be lytic and no lysogenic state could be demonstrated. Electron micrographs showed that the phages were morphologically identical and had polyhedral heads and contractile tails. Their genomes were sensitive to restriction enzymes and consisted of double-stranded DNA. Pulsed-field agarose gel electrophoresis indicated that their genomes were linear: 60 kb for LE1 and 50 kb for LE3 and LE4.

References

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Citations

Jul 1, 1992·Research in Microbiology·S BergströmJ MacDougall
Jul 27, 2001·FEMS Microbiology Letters·A BrenotI Saint Girons
Feb 3, 2005·Nature Reviews. Microbiology·Patricia A RosaPhilip E Stewart
Sep 17, 2009·Nature Reviews. Microbiology·Albert I KoMathieu Picardeau
Jun 1, 2010·Applied and Environmental Microbiology·Dante PoggiMathieu Picardeau
Nov 13, 2007·Applied and Environmental Microbiology·Mathieu Picardeau
Jul 24, 2001·Journal of Bacteriology·C H EggersD S Samuels
Aug 20, 2005·Journal of Bacteriology·Eric G MatsonThad B Stanton
Nov 13, 2012·PLoS Neglected Tropical Diseases·Jessica N RicaldiMichael A Matthias
Sep 24, 2010·Future Microbiology·Karen V Evangelista, Jenifer Coburn
Aug 2, 2003·FEMS Microbiology Letters·Thad B StantonRichard L Zuerner
Dec 1, 1995·FEMS Microbiology Letters·S B HumphreyN S Jensen
Feb 20, 2016·PLoS Neglected Tropical Diseases·Derrick E FoutsJoseph M Vinetz
Aug 8, 2018·Scientific Reports·Olivier SchiettekattePascale Bourhy
Mar 17, 2009·Journal of Molecular Biology·Charles R StewartMarisa L Pedulla

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