First report of Cytauxzoon sp. infection in Germany: organism description and molecular confirmation in a domestic cat

Parasitology Research
Luciana Cătălina PanaitNikola Pantchev

Abstract

Cytauxzoonosis is described as an emerging tick-borne disease of domestic and wild felids caused by protozoans of the genus Cytauxzoon. While in the Americas the condition is described as a fatal disease, in Europe, reports on the clinical expression of the infection are scarce. This study describes the first case of Cytauxzoon sp. infection in Germany, in a domestic cat. A 6-year-old male domestic cat living in Saarlouis (Saarland) was presented with anorexia, lethargy and weight loss. The cat had an outdoor lifestyle and had not travelled abroad. Serum clinical chemistry analysis revealed azotaemia with markedly increased symmetric dimethylarginine, hypercreatinemia, hyperphosphatemia and hypoalbuminemia. Moreover, a mild non-regenerative anaemia was present. Approximately 1 year prior to these findings, the domestic cat was diagnosed with a feline immunodeficiency virus (FIV) infection. These results pointed toward a decreased glomerular filtration rate, presumably as a result of kidney dysfunction. Round to oval signet ring-shaped intraerythrocytic organisms, morphologically suggestive for a piroplasm, were revealed during blood smear evaluation with a degree of parasitaemia of 33.0%. PCR analyses and sequencing of a region...Continue Reading

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Citations

Jan 20, 2021·Veterinary Parasitology·Luciana Cătălina PanaitKristýna Hrazdilová
Aug 12, 2021·Clinical Microbiology Reviews·Simone MorelliDonato Traversa

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Datasets Mentioned

BETA
MN629916
EU622908

Methods Mentioned

BETA
ELISA
PCR
electrophoresis

Software Mentioned

Basic Local Alignment Search Tool ( BLAST )
^ F
BLAST
Cell

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