Abstract
This study reports the first full length gene of interferon related developmental regulator-1 (designated as MrIRDR-1), identified from the transcriptome of Macrobrachium rosenbergii. The complete gene sequence of the MrIRDR-1 is 2459 base pair long with an open reading frame of 1308 base pairs and encoding a predicted protein of 436 amino acids with a calculated molecular mass of 48 kDa. The MrIRDR-1 protein contains a long interferon related developmental regulator super family domain between 30 and 330. The mRNA expressions of MrIRDR-1 in healthy and the infectious hypodermal and hematopoietic necrosis virus (IHHNV) infected M. rosenbergii were examined using qRT-PCR. The MrIRDR-1 is highly expressed in hepatopancreas along with all other tissues (walking leg, gills, muscle, haemocyte, pleopods, brain, stomach, intestine and eye stalk). After IHHNV infection, the expression is highly upregulated in hepatopancreas. This result indicates an important role of MrIRDR-1 in prawn defense system.
References
Sep 9, 1988·Cell·M MiyamotoT Taniguchi
Aug 13, 1993·Cell·A B Sachs
Jun 17, 1994·Cell·N TanakaT Taniguchi
Jun 24, 1994·Science·T KimuraT W Mak
Jun 25, 1993·Nucleic Acids Research·S KirchhoffH Hauser
Aug 29, 1996·Nature·N TanakaT Taniguchi
Sep 2, 1998·Genomics·P BuanneF Tirone
Oct 6, 1998·Annual Review of Biochemistry·G R StarkR D Schreiber
Jul 30, 1999·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·A Eroshkin, A Mushegian
Sep 7, 2001·Annual Review of Microbiology·G C Sen
Feb 16, 2002·Methods : a Companion to Methods in Enzymology·K J Livak, T D Schmittgen
Feb 16, 2002·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Betsy BarnesPaula M Pitha
Oct 22, 2004·Nature Immunology·Paul D Bieniasz
Jun 9, 2005·Fish & Shellfish Immunology·Børre Robertsen
Jun 30, 2006·Fish & Shellfish Immunology·A J A McBeathB Collet
Aug 5, 2006·Developmental and Comparative Immunology·Yi-Bing ZhangJian-Fang Gui
Apr 3, 2007·Biochimie·A Paun, P M Pitha
Mar 20, 2009·Molecular Immunology·Arun K DharBetsy Read
Mar 26, 2009·BioFactors·Volker Fensterl, Ganes C Sen
Aug 18, 2010·Fish & Shellfish Immunology·Guobin HuQiuming Liu
Dec 15, 2010·Developmental and Comparative Immunology·Guobin HuXianzhi Dong
Citations
Jun 5, 2013·PloS One·Maizatul Izzah Mohd-ShamsudinSubha Bhassu
Oct 17, 2012·Fish & Shellfish Immunology·Jesu ArockiarajSubha Bhassu
Jul 4, 2012·Fish & Shellfish Immunology·Jesu ArockiarajSubha Bhassu
May 15, 2013·Microbiological Research·Jesu ArockiarajMarimuthu Kasi
Aug 21, 2012·Gene·Jesu ArockiarajSubha Bhassu
Apr 26, 2016·Fish & Shellfish Immunology·Mukesh Kumar ChaurasiaJesu Arockiaraj
Jun 27, 2017·Fish & Shellfish Immunology·Qianqian GeQianqian Zhai
Aug 11, 2021·Scientific Reports·Xue LiuKeyi Ma