May 16, 2020

First report on multidrug-resistant non-encapsulated Streptococcus pneumoniae isolated from a patient with pneumonia

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Noriko TakeuchiNaruhiko Ishiwada

Abstract

The non-encapsulated Streptococcus pneumoniae (NESp) has emerged and increased in the clinical setting. The majority of NESp strains have been isolated from the nasopharynxes of healthy carriers and from respiratory specimens of patients with otitis media. NESp strains were shown to be more effective than encapsulated counterparts at forming biofilms. Therefore, NESp should become one of the leading causes of emerging refractory respiratory disease after the introduction of pneumococcal conjugate vaccines. We report the first case of multidrug-resistant - including fluoroquinolone-resistant - NESp isolated from the intrabronchial aspirate of a patient with pneumonia. Drug-resistant NESp infections can possibly emerge as a clinical problem and thus the continuous monitoring of NESp infections is of utmost importance.

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Mentioned in this Paper

Respiration Disorders
Nasopharynx
Fluoroquinolones
Genetic Carriers
Pneumonia
Streptococcus pneumoniae
Monitoring - Action
Pneumococcal conjugate vaccine
Pneumococcal Infections
Drug Resistance

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