First report on the nationwide incidence of type 1 diabetes and ketoacidosis at onset in children in Serbia: a multicenter study

European Journal of Pediatrics
Rade VukovicIvan Soldatovic

Abstract

Data regarding incidence of type 1 diabetes (T1DM), as well as data on frequency and severity of diabetic ketoacidosis (DKA) at the time of T1DM diagnosis is of paramount importance for national and regional healthcare planning. The aim of present multicenter study was to provide the first report regarding nationwide annual incidence rates for T1DM in youth in Serbia, as well as prevalence of DKA at the time of diagnosis. Data on all pediatric patients with newly diagnosed T1DM was retrospectively collected from all 15 regional centers for pediatric diabetes in Serbia during the period 2007-2017. During the study period, average-standardized incidence of T1DM in youth < 19 years was 11.82/100,000, and 14.28/100,000 in 0-14 years age group, with an average yearly increase in incidence of 5.9%. High prevalence of DKA (35.1%) at the time of diagnosis was observed, with highest frequency in children aged < 5 years (47.2%). This is the first study reporting the nationwide incidence of T1DM and alarmingly high prevalence of DKA at diagnosis in youth in Serbia. The focus of public health preventive measures should be directed towards the preschoolers, considering the highest frequency and severity of DKA observed in this age group. Wh...Continue Reading

References

Feb 1, 1995·Journal of Epidemiology and Community Health·H D VlajinacD S Zdravković
Sep 18, 1999·Archives of Disease in Childhood·J A EdgeD B Dunger
Nov 29, 2001·Diabetologia·C Lévy-MarchalUNKNOWN EURODIAB ACE Study Group. Europe and Diabetes
Jul 1, 1960·Annals of Human Genetics·A W EDWARDS, M FRACCARO
Dec 6, 2003·Pediatric Diabetes·Andreas NeuUNKNOWN DIARY Group Baden-Wuerttemberg
May 25, 2004·Archives of Disease in Childhood·S EhtishamUNKNOWN British Society for Paediatric Endocrinology and Diabetes Clinical Trials Group
Jun 21, 2005·Pediatric Diabetes·Mark A Sperling
Apr 18, 2006·The Journal of Pediatrics·Maryanne QuinnJoseph I Wolfsdorf
Aug 17, 2006·Diabetic Medicine : a Journal of the British Diabetic Association·UNKNOWN DIAMOND Project Group
Jun 28, 2007·JAMA : the Journal of the American Medical Association·UNKNOWN Writing Group for the SEARCH for Diabetes in Youth Study GroupBeth Waitzfelder
Dec 8, 2009·The Journal of Pediatrics·Helen BuiDenis Daneman
Aug 21, 2010·Endocrinology and Metabolism Clinics of North America·David M MaahsElizabeth J Mayer-Davis
Dec 7, 2010·Pediatric Diabetes·Agnieszka Szypowska, Agata Skórka
Jan 25, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·R VukovicD Zdravkovic
Dec 18, 2013·Diabetes Research and Clinical Practice·Chris PattersonMartin Silink
Oct 16, 2015·Current Diabetes Reports·Jeffrey W Kleinberger, Toni I Pollin

❮ Previous
Next ❯

Citations

Oct 11, 2019·Archives of Disease in Childhood·Ivana RabboneUNKNOWN Diabetes Study Group of the Italian Society for Pediatric Endocrinology and Diabetology (ISPED)
Nov 27, 2018·Clinical Nursing Research·Hamdiye Arda SürücüEngin Turan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Autoimmune Diabetes & Tolerance

Patients with type I diabetes lack insulin-producing beta cells due to the loss of immunological tolerance and autoimmune disease. Discover the latest research on targeting tolerance to prevent diabetes.