First seizure: EEG and neuroimaging following an epileptic seizure

Epilepsia
Bernd Pohlmann-Eden, Mark R Newton

Abstract

An early EEG (within 48 h) and high-resolution magnetic resonance imaging (hr_MRI) are the methods of choice for an accurate diagnosis after a first seizure presentation. Together with a careful history and examination, they will allow definition of the epilepsy syndrome in two-thirds of patients and help assess the individual risk for seizure recurrence, which is determined by the specific syndrome and is highest with focal epileptiform activity on EEG. Despite the heterogeneity of first seizure studies, EEG and etiology are consistently found to be the best predictors for seizure recurrence and prognosis. The additional yield of sleep-deprived EEG and sleep EEG is uncertain; yet MRI is essential for detecting brain tumors and other structural bases for new epilepsy. The rate occurrence of remote symptomatic seizures increases significantly with age and the most common etiology in the elderly with a first seizure is stroke; however, its exact relevance to epileptogenicity is yet to be defined. There is a striking lack of systematic studies using early EEG and hr_MRI in order to better characterize epileptogenic areas and elucidate the mechanisms of seizure provocation.

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Citations

Jul 16, 2011·Epilepsia·Bernd Pohlmann-Eden
Aug 25, 2011·Epilepsia·Ryan C N D'ArcyDavid B Clarke
Sep 7, 2012·Epilepsy Research and Treatment·Colin Bruce Josephson, Bernhard Pohlmann-Eden
Jun 1, 2010·Continuum : Lifelong Learning in Neurology·Matthew T HoerthJoseph I Sirven
Jun 19, 2013·Journal of Pediatric Neurosciences·Arif Khan, Aravindhan Baheerathan
Jan 23, 2014·Irish Journal of Medical Science·D A Olszewska, D J Costello
Dec 2, 2014·Neurophysiologie clinique = Clinical neurophysiology·N André-ObadiaM D Lamblin
Sep 13, 2015·Seizure : the Journal of the British Epilepsy Association·Prakash PaliwalRahul Rathakrishnan
Oct 26, 2010·Acta Neurologica Scandinavica·R Gandelman-Marton, J Theitler
May 20, 2014·Seizure : the Journal of the British Epilepsy Association·James B LillekerRajiv Mohanraj
Aug 14, 2015·Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række·Martha Seim RealfsenKarl O Nakken
Apr 30, 2013·Seizure : the Journal of the British Epilepsy Association·Jessica Askamp, Michel J A M van Putten
May 1, 2013·Seizure : the Journal of the British Epilepsy Association·Fawzi A Babtain
Jul 6, 2010·Seizure : the Journal of the British Epilepsy Association·M HeersH Stefan
Jul 11, 2013·Seizure : the Journal of the British Epilepsy Association·James B LillekerRajiv Mohanraj
Feb 2, 2015·Neurophysiologie clinique = Clinical neurophysiology·V MichelL Vercueil
Jun 22, 2016·Seizure : the Journal of the British Epilepsy Association·Candice E CrockerMatthias H Schmidt
Apr 10, 2013·Journal of Neuroscience Methods·Jalil RasekhiAntonio Dourado
Oct 18, 2016·Annals of Emergency Medicine·Andrew J WymanAndrew W Asimos
Mar 1, 2017·Seizure : the Journal of the British Epilepsy Association·Syed RizviJosé F Téllez-Zenteno
Oct 11, 2016·Seizure : the Journal of the British Epilepsy Association·Karen T Legg, Mark Newton
Feb 23, 2017·Seizure : the Journal of the British Epilepsy Association·Bernd Pohlmann-Eden, Jorge G Burneo
Jul 1, 2009·Expert Review of Clinical Pharmacology·Armel StockisChristian Otoul
Sep 9, 2016·Journal of Neurology·L FischM Seeck
Nov 3, 2020·Journal of Neuroscience Methods·Wendong GeM Brandon Westover
May 28, 2021·Epilepsy & Behavior Reports·Tasneem F Hasan, William O Tatum
Aug 3, 2021·Curēus·Muhammad A KhalilyAreeba Wasim
Sep 9, 2021·Developmental Medicine and Child Neurology·Nicola Specchio, Alessandro Ferretti

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