First-Trimester Fetal Echocardiography: Identification of Cardiac Structures for Screening from 6 to 13 Weeks' Gestational Age

Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Darren HutchinsonLisa K Hornberger

Abstract

Early fetal echocardiography (FE), performed at 12 to 16 weeks' gestational age (GA), can be used to screen for fetal heart disease akin to that routinely performed in the second trimester. The efficacy of FE at earlier GAs has not been as well explored, particularly with recent advances in ultrasound technology. The aim of this study was to evaluate the efficacy of early FE in assessing fetal heart structure, and the added benefit of color Doppler (CD), from as early as 6 weeks through to 13+6 weeks' GA. Pregnant women were prospectively recruited for first-trimester FE. All underwent two-dimensional (2D) cardiac imaging combined with CD assessment, and all were offered second-trimester fetal echocardiographic evaluations. Fetal cardiac anatomy was assessed both in real time during FE and additionally offline by two separate reviewers. Very early FE was performed in 202 pregnancies including a total of 261 fetuses, with 92% (n = 241) being reassessed at ≥18 weeks' GA. Mean GA at FE was 10+6 weeks (range, 6+1 to 13+6 weeks). Transabdominal scanning was used in all cases, and transvaginal scanning was used additionally in most at <11 weeks' GA (n = 103 of 117 [88%]). There was stepwise improvement in image resolution of the feta...Continue Reading

Citations

Nov 16, 2018·Birth Defects Research·Angela McBrien, Lisa K Hornberger
Dec 19, 2018·Circulation. Cardiovascular Imaging·Luke G Eckersley, Lisa K Hornberger
Feb 12, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·F G Sileo, J S Carvalho
Sep 9, 2019·Journal of Perinatal Medicine·Alaa EbrashyMohamed Momtaz
Jun 6, 2020·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Catalin Gabriel HerghelegiuAlina Veduta
Aug 28, 2020·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine
Apr 9, 2020·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Heba Kamel, Amr Yehia
Apr 20, 2021·Journal of Healthcare Engineering·Canliang WenHongye Jiang
May 18, 2021·Ultrasound : Journal of the British Medical Ultrasound Society·Stephanie F SmithChristoph Lees

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Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

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