PMID: 15226460Jul 1, 2004Paper

Fish consumption shifts lipoprotein subfractions to a less atherogenic pattern in humans

The Journal of Nutrition
Zhengling LiE J Schaefer

Abstract

The effect of fish consumption on plasma lipoprotein subfraction concentrations was studied in 22 men and women (age > 40 y). Subjects were provided an average American diet (AAD, 35% of energy as fat, 14% as saturated fat, and 35 mg cholesterol/MJ) for 6 wk before being assigned to a National Cholesterol Education Program (NCEP) Step 2 high-fish diet (n = 11, 26% of energy as fat, 4.5% as saturated fat, and 15 mg cholesterol/MJ) or a NCEP Step 2 low-fish diet (n = 11, 26% of energy as fat, 4.0% as saturated fat, and 11 mg cholesterol/MJ) for 24 wk. All food and drink were provided to study participants. Consumption of the high-fish NCEP Step 2 diet was associated with a significant reduction in medium and small VLDL, compared with the AAD diet, whereas the low-fish diet did not affect VLDL subfractions. Both diets significantly reduced LDL cholesterol concentrations, without modifying LDL subfractions. Both diets also lowered HDL cholesterol concentrations. However, the high-fish diet significantly lowered only the HDL fraction containing both apolipoprotein (apo) AI and AII (LpAI:AII) and did not change HDL subfractions assessed by NMR, whereas the low-fish diet significantly lowered the HDL fraction containing only apo AI (L...Continue Reading

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Citations

Jun 25, 2005·Diabetic Medicine : a Journal of the British Diabetic Association·R L KennedyH R Farshchi
May 13, 2008·The American Journal of Clinical Nutrition·Elizabeth J JohnsonD Max Snodderly
Dec 7, 2016·The Proceedings of the Nutrition Society·Yiyi Ma, Jose M Ordovas
Aug 11, 2018·Open Heart·James J DiNicolantonio, James H O'Keefe
Feb 28, 2020·Journal of the American Heart Association·Nuria AmigóSamia Mora
Feb 22, 2005·Preventive Cardiology·Sonia Vega-López, Alice H Lichtenstein
Aug 22, 2012·Annals of Nutrition & Metabolism·Hiroya HidakaTakayuki Honda
Jul 12, 2017·Journal of Nutrition and Metabolism·Lotte SmoldersRonald P Mensink
Dec 20, 2017·The Journal of Nutritional Biochemistry·Petr ŽáčekMatthew Picklo
Oct 11, 2005·The Journal of Nutritional Biochemistry·Yolanda B Lombardo, Adriana G Chicco

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