Fish, fish-derived n-3 fatty acids, and risk of incident atrial fibrillation in the Atherosclerosis Risk in Communities (ARIC) study.

PloS One
Noelle N GronroosAlvaro Alonso

Abstract

Results of observational and experimental studies investigating the association between intake of long-chain n-3 polyunsaturated fatty acids (PUFAs) and risk of atrial fibrillation (AF) have been inconsistent. We studied the association of fish and the fish-derived n-3 PUFAs eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) with the risk of incident AF in individuals aged 45-64 from the Atherosclerosis Risk in Communities (ARIC) cohort (n = 14,222, 27% African Americans). Intake of fish and of DHA and EPA were measured via food frequency questionnaire. Plasma levels of DHA and EPA were measured in phospholipids in a subset of participants (n = 3,757). Incident AF was identified through the end of 2008 using ECGs, hospital discharge codes and death certificates. Cox proportional hazards regression was used to estimate hazard ratios of AF by quartiles of n-3 PUFAs or by fish intake. During the average follow-up of 17.6 years, 1,604 AF events were identified. In multivariable analyses, total fish intake and dietary DHA and EPA were not associated with AF risk. Higher intake of oily fish and canned tuna was associated with a nonsignificant lower risk of AF (p for trend = 0.09). Phospholipid levels of DHA+EPA were not relat...Continue Reading

References

Jan 1, 1992·Alzheimer Disease and Associated Disorders·A J LernerP J Whitehouse
Jan 1, 1987·Cancer Investigation·A C Hollinshead
Jul 1, 1986·American Journal of Epidemiology·W Willett, M J Stampfer
Jul 1, 1985·American Journal of Epidemiology·W C WillettF E Speizer
Jul 1, 1993·Journal of the American Dietetic Association·D FeskanichW C Willett
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·Y F XiaoA Leaf
Mar 19, 2003·Circulation·Dariush MozaffarianUNKNOWN Cardiovascular Health Study
Jul 21, 2004·Circulation·Dariush MozaffarianDavid S Siscovick
Jan 11, 2005·The American Journal of Clinical Nutrition·Lars Frost, Peter Vestergaard
May 17, 2005·Journal of the American College of Cardiology·Leonardo CalòMassimo Santini
Nov 10, 2005·European Heart Journal·Christopher J BoosGregory Y H Lip
Jan 31, 2006·The American Journal of Cardiology·Dariush MozaffarianDavid S Siscovick
Feb 25, 2006·European Heart Journal·Demosthenes G Katritsis
Mar 30, 2006·American Heart Journal·Ingeborg A BrouwerJacqueline C M Witteman
Jul 18, 2006·The American Journal of Clinical Nutrition·Jan L Breslow
Sep 2, 2006·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·K Ganesh KumarBrenda K Smith Richards
Oct 19, 2006·JAMA : the Journal of the American Medical Association·Dariush Mozaffarian, Eric B Rimm
Feb 17, 2007·Pacing and Clinical Electrophysiology : PACE·Eivind SolheimJian Chen
Feb 21, 2008·Circulation·Dariush MozaffarianDavid S Siscovick
Jun 11, 2008·The American Journal of Clinical Nutrition·Dariush Mozaffarian
Nov 27, 2008·Journal of the National Cancer Institute·Victor Kipnis, Laurence S Freedman
Jan 12, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Ragnhildur HeidarsdottirOlafur S Indridason
Feb 18, 2010·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Chiara Viviani AnselmiAnnibale Alessandro Puca
Mar 10, 2010·The American Journal of Cardiology·Jarett D BerryDonald M Lloyd-Jones
Jul 20, 2010·Prostaglandins, Leukotrienes, and Essential Fatty Acids·J DyerbergE B Schmidt
Sep 15, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·Noelle N Gronroos, Alvaro Alonso
Nov 26, 2010·The American Journal of Clinical Nutrition·Jian ShenEmelia J Benjamin
Dec 17, 2010·Circulation·Véronique L RogerUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Nov 29, 2011·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Saurabh KumarPaul B Sparks

❮ Previous
Next ❯

Citations

Feb 28, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Thomas A RixKim Overvad
Dec 1, 2012·Current Opinion in Clinical Nutrition and Metabolic Care·Thomas A RixErik B Schmidt
Sep 25, 2015·International Journal of Molecular Sciences·Georgios A ChristouJohn A Goudevenos
Mar 26, 2013·Journal of the American Heart Association·Devera W Kastner, David R Van Wagoner
May 3, 2014·Circulation·Miguel Á Martínez-GonzálezUNKNOWN PREDIMED Investigators
Apr 26, 2019·Journal of the American Heart Association·Shaozhao ZhangXinxue Liao
Jan 31, 2018·Critical Reviews in Food Science and Nutrition·GianLuca ColussiLeonardo A Sechi
Jun 25, 2017·Annual Review of Nutrition·Dong D Wang, Frank B Hu
Jan 3, 2020·Circulation Research·JoAnn E MansonUNKNOWN VITAL Research Group

❮ Previous
Next ❯

Software Mentioned

SAS

Related Concepts

Related Feeds

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Atrial Filbrillation

Atrial fibrillation refers to the abnormal heart rhythm characterized by rapid and irregular beating of the atria. Here is the latest research.

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Related Papers

International Journal of Cardiology
Leonardo CalòClaudia Tota
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Thomas Andersen RixKim Overvad
© 2021 Meta ULC. All rights reserved