Fish oil in critical illness: mechanisms and clinical applications.

Critical Care Clinics
Renee D StapletonKonstantin Mayer

Abstract

Fish oil is rich in omega-3 fatty acids, which have been shown to be beneficial in multiple disease states that involve an inflammatory process. It is now hypothesized that omega-3 fatty acids may decrease the inflammatory response and be beneficial in critical illness. After a review of the mechanisms of omega-3 fatty acids in inflammation, research using enteral nutrition formulas and parenteral nutrition lipid emulsions fortified with fish oil were examined. The results of this research to date are inconclusive for both enteral and parenteral omega-3 fatty acid administration. More research is required before definitive recommendations can be made on fish oil supplementation in critical illness.

References

Nov 30, 1983·Biochemical and Biophysical Research Communications·D W GoldmanE J Goetzl
May 1, 1997·The Journal of Trauma·J R SaffleR G Barton
Apr 1, 1997·Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS·J M EngelG Hempelmann
Dec 23, 1999·Chemical Immunology·H D VolkW D Döcke
May 12, 2000·Critical Care Medicine·E M Bulger, R V Maier
Jul 4, 2001·The Journal of Clinical Investigation·S L TilleyB H Koller
Aug 31, 2001·JAMA : the Journal of the American Medical Association·D K HeylandU Suchner
Feb 28, 2002·Trends in Immunology·Sarah G HarrisRichard P Phipps
Mar 16, 2002·The British Journal of Nutrition·G WeissH Lippert
Dec 20, 2002·Nature·Jonathan Cohen
Jan 10, 2003·The New England Journal of Medicine·Richard S Hotchkiss, Irene E Karl
Feb 21, 2003·Intensive Care Medicine·Jean-Charles PreiserUNKNOWN ESICM(European Society of Intensive Care Medicine) Working Group on Nutrition and Metabolism
Mar 5, 2003·American Journal of Respiratory and Critical Care Medicine·Konstantin MayerFriedrich Grimminger
Apr 1, 2003·JPEN. Journal of Parenteral and Enteral Nutrition·Jeffrey L NelsonUNKNOWN Enteral Nutrition in ARDS Study Group
Sep 16, 2003·JPEN. Journal of Parenteral and Enteral Nutrition·Daren K HeylandUNKNOWN Canadian Critical Care Clinical Practice Guidelines Committee
Feb 7, 2004·Nature·Jing X KangZhao B Kang
Feb 1, 1990·The Journal of Nutritional Biochemistry·M G Murphy
Feb 9, 2005·The American Journal of Clinical Nutrition·Anouk GeelenPeter L Zock
Mar 9, 2005·The Journal of Experimental Medicine·Makoto AritaCharles N Serhan
May 14, 2005·Proceedings of the National Academy of Sciences of the United States of America·Makoto AritaCharles N Serhan
May 17, 2005·Journal of the American College of Cardiology·Leonardo CalòMassimo Santini
Feb 18, 2006·Critical Care Medicine·Axel R HellerThea Koch
Sep 26, 2006·Journal of Burn Care & Research : Official Publication of the American Burn Association·Lucy A WibbenmeyerPatrick G Kealey
Oct 24, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Burkhard MichaeliRené Chioléro
Dec 22, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Bruce D LevyCharles N Serhan
Mar 6, 2007·Trends in Immunology·Amiram Ariel, Charles N Serhan
Mar 7, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Makoto AritaCharles N Serhan

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Citations

May 24, 2011·Current Gastroenterology Reports·Craig MunroeStephen A McClave
May 7, 2011·Archives of Pharmacal Research·Dong-Soon Im
Feb 16, 2013·The Proceedings of the Nutrition Society·Nikki BuijsPaul A M van Leeuwen
Jan 9, 2013·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Brian R JacobsUNKNOWN Nutritional Immunomodulation in Children with Lung Injury (NICLI) Study Group
Apr 27, 2011·Seminars in Dialysis·Enrico FiaccadoriGiuseppe Regolisti
Jun 3, 2015·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Stacey L ValentineUNKNOWN Pediatric Acute Lung Injury Consensus Conference Group
Jul 29, 2011·Prostaglandins, Leukotrienes, and Essential Fatty Acids·M Bernabe-GarciaJ L Arredondo-García
Oct 3, 2013·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Ning-Ning LiXiao-Ting Wu
Apr 24, 2013·JPEN. Journal of Parenteral and Enteral Nutrition·William ManzanaresDaren K Heyland
Jun 19, 2016·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Emily J McCleary, Sharla Tajchman
Dec 18, 2012·Current Opinion in Clinical Nutrition and Metabolic Care·Enrico FiaccadoriUmberto Maggiore
Jul 8, 2011·Current Opinion in Anaesthesiology·Paul Wischmeyer
May 14, 2021·The Journal of International Medical Research·Yi-Ling WangChien-Chou Hsiao
Dec 26, 2018·Journal of the American Medical Directors Association·Nicolaas E P DeutzCarla M Prado
Jul 8, 2011·Current Opinion in Anaesthesiology

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