Five Keratoplasties From One Donor Cornea

Cornea
Oganes G OganesyanVostan R Getadaryan

Abstract

To describe the feasibility of same-day, consecutive use of a single donor cornea in 5 patients with corneal pathology, who required anterior lamellar and endothelial keratoplasties. Descemet membrane (DM) with endothelium was completely stripped from a single corneoscleral button and punched out from the endothelial side with a circular, standard punch. Using a custom-made punch for linear cutting of DM, we obtained 4 quarter-grafts (Q-graft). The denuded and punched-out corneal stroma was transplanted in 1 patient with keratoconus, using the big-bubble deep anterior lamellar keratoplasty (DALK) technique. The 4 DM Q-grafts were consecutively transplanted to 4 patients with Fuchs dystrophy using the quarter Descemet membrane endothelial keratoplasty (Q-DMEK or 1/4 DMEK) technique. All surgical procedures were performed successfully during 1 surgical session. No intraoperative or postoperative complications requiring intervention were observed. Six months after surgery, the decimal best-corrected visual acuity achieved was 0.66 after DALK and 0.95 ± 0.1 (range, 0.8-1.0) in the 4 Q-DMEK cases; the endothelial cell density was 1680 ± 254 cells/mm (range, 1492-2039 cells/mm). Six months postoperatively, all corneas were clear. In ...Continue Reading

References

Dec 24, 2002·Developments in Ophthalmology·T M M H de By
Nov 15, 2006·Cornea·Gerrit R J Melles
Apr 11, 2007·Archives of Ophthalmology·Rasik B VajpayeeRadhika Tandon
Jan 27, 2009·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Mahta RasouliAllan R Slomovic
Aug 3, 2011·Cornea·Namrata SharmaRasik B Vajpayee
Dec 4, 2015·JAMA Ophthalmology·Philippe GainGilles Thuret
Feb 4, 2016·The British Journal of Ophthalmology·Nadine Gerber-HollbachGerrit Rj Melles

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Citations

Oct 31, 2020·Acta Ophthalmologica·Oganes OganesyanGerrit R J Melles
Sep 19, 2020·Cornea·Kunal A GadhviVito Romano
Feb 25, 2021·International Ophthalmology·Adriano FasoloGiorgio Marchini
Jul 27, 2021·Journal of Ophthalmology·Carlos Rocha-de-LossadaMarina Rodríguez Calvo-de-Mora

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