Five Year Follow-up of a Randomized Controlled Trial of Laparoscopic Repair of Very Large Hiatus Hernia With Sutures Versus Absorbable Versus Nonabsorbable Mesh.

Annals of Surgery
David I WatsonGlyn G Jamieson

Abstract

To determine whether absorbable or nonabsorbable mesh repair of large hiatus hernias is followed by less recurrences at late follow-up compared to sutured repair. Radiological recurrences have been reported in up to 30% of patients after repair of large hiatus hernias, and mesh repair has been proposed as a solution. Earlier trials have revealed mixed outcomes and early outcomes from a trial reported previously revealed no short-term advantages for mesh repair. Multicentre prospective double-blind randomized controlled trial of 3 methods of hiatus hernia repair; sutures versus absorbable mesh versus nonabsorbable mesh. Primary outcome - hernia recurrence assessed by barium meal X-ray and endoscopy at 3-4 years. Secondary outcomes - clinical symptom scores at 2, 3, and 5 years. 126 patients were enrolled - 43 sutures, 41 absorbable mesh, and 42 nonabsorbable mesh. Clinical outcomes were obtained at 5 years in 89.9%, and objective follow-up was obtained in 72.3%. A recurrent hernia (any size) was identified in 39.3% after suture repair, 56.7% - absorbable mesh, and 42.9% - nonabsorbable mesh (P = 0.371). Clinical outcomes were similar at 5 years, except chest pain, diarrhea, and bloat symptoms which were more common after repair ...Continue Reading

References

Mar 1, 1992·Journal of Clinical Gastroenterology·M Dakkak, J R Bennett
May 9, 2000·Journal of the American College of Surgeons·M HashemiC G Bremner
Apr 1, 2005·The British Journal of Surgery·A AlyD I Watson
Nov 15, 2007·Surgical Endoscopy·G S SmithC J Martin
Jan 24, 2008·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Bas P L Wijnhoven, David I Watson
Dec 10, 2009·Surgical Endoscopy·Constantine T FrantzidesAlexander Frantzides
Mar 31, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Zhenyu WangDavid I Watson

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Citations

Jun 20, 2020·Surgical Endoscopy·Calista SpiroSiva Gananadha
Nov 10, 2020·ANZ Journal of Surgery·Felix LeeGregory Falk
Jan 21, 2021·Asian Journal of Endoscopic Surgery·Fumiaki YanoToru Ikegami
Jan 6, 2021·Surgical Endoscopy·Shunsuke TanabeToshiyoshi Fujiwara
Jul 28, 2020·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Merel LubbersMarc J van Det
Apr 3, 2021·World Journal of Gastrointestinal Surgery·Christoph G DietrichJoachim W Heise
Apr 15, 2021·Zentralblatt für Chirurgie·Jasmina Kuvendjiska, Jens Höppner
Sep 11, 2021·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Yalini VigneswaranJohn Alverdy
Aug 3, 2021·Annals of Surgery·Hugo HertaultGuillaume Piessen

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