Fixation instability during binocular viewing in anisometropic and strabismic children.

Experimental Eye Research
Krista R KellyEileen E Birch

Abstract

Strabismus or anisometropia disrupts binocularity and results in fixation instability, which is increased with amblyopia. Fixation instability has typically been assessed for each eye individually. Recently, vergence instability was reported in exotropic adults and monkeys during binocular viewing. We evaluated fixation instability during binocular viewing in children treated for anisometropia and/or strabismus. 160 children age 4-12 years with treated esotropia and/or anisometropia (98 amblyopic, 62 nonamblyopic) were compared to 46 age-similar controls. Fixation instability was recorded during binocular fixation of a 0.3 deg diameter dot for 20 s using a 500 Hz remote video binocular eye tracker (EyeLink 1000; SR Research). The bivariate contour ellipse area (BCEA; log deg2) for fixation instability was calculated for each eye (nonpreferred, preferred) and for vergence instability (left eye position - right eye position). Best-corrected visual acuity, Randot Preschool stereoacuity, and extent of suppression scotoma (Worth 4-Dot) were also obtained. When binocularly viewing, both amblyopic and nonamblyopic children treated for anisometropia and/or strabismus had larger fixation instability and vergence instability than control...Continue Reading

Citations

Apr 13, 2019·Journal of Vision·Maciej PerdziakJan Ober
Jun 5, 2019·Journal of Binocular Vision and Ocular Motility·Eileen E BirchDeborah E Giaschi
Jun 4, 2019·Seminars in Ophthalmology·Eric D GaierGena Heidary
Jul 10, 2019·Neural Plasticity·Ewa Niechwiej-SzwedoAgnes M F Wong
Nov 19, 2020·Journal of Binocular Vision and Ocular Motility·Nathaniel P MillerBas Rokers
Sep 10, 2021·Ophthalmology and Therapy·Eileen E BirchJingyun Wang

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